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Hand2os1 Gene Detail
Summary
  • Symbol
    Hand2os1
  • Name
    Hand2, opposite strand 1
  • Synonyms
    AV026068, Gm28063, Hand2-as1, Uph, upperhand
Location &
Maps
more
  • Sequence Map
    Chr8:57757296-57773894 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5578769
 antisense lncRNA gene Chr8:57734152-57782056 (-)
129S1/SvImJ ENSMUSG00200008039
 lncRNA gene Chr8:52522339-52565142 (-)
A/J ENSMUSG00195012486
 lncRNA gene Chr8:52923864-52966670 (-)
AKR/J ENSMUSG00220006092
 lncRNA gene Chr8:52745636-52788592 (-)
BALB/cJ ENSMUSG00180014502
 lncRNA gene Chr8:52575864-52618794 (-)
C3H/HeJ ENSMUSG00175007880
 lncRNA gene Chr8:52753121-52796051 (-)
C57BL/6NJ ENSMUSG00215008894
 lncRNA gene Chr8:52539406-52582522 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013837
 unclassified non-coding RNA gene Chr8:50170582-50187068 (-)
CAST/EiJ ENSTCUG00005006704
 lncRNA gene Chr8:52494096-52536185 (-)
CBA/J ENSMUSG00210009384
 lncRNA gene Chr8:52598039-52640841 (-)
DBA/2J ENSMUSG00185008166
 lncRNA gene Chr8:58735155-58778089 (-)
FVB/NJ ENSMUSG00205011715
 lncRNA gene Chr8:51990080-52033014 (-)
JF1/MsJ ENSUMUG00000011606
 lncRNA gene Chr8:61063695-61105803 (-)
LP/J ENSMUSG00230007755
 lncRNA gene Chr8:62394214-62437137 (-)
NOD/ShiLtJ ENSMUSG00190010358
 lncRNA gene Chr8:52519295-52562092 (-)
NZO/HlLtJ ENSMUSG00225031482
 lncRNA gene Chr8:65821341-65864145 (-)
PWK/PhJ ENSLUMG00010013189
 lncRNA gene Chr8:52434404-52476436 (-)
SPRET/EiJ ENSMSPG00010014889
 lncRNA gene Chr8:53512985-53555783 (-)
WSB/EiJ ENSIUOG00005017122
 lncRNA gene Chr8:53441543-53484687 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 5 alleles in 3 genetic backgrounds
    4 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozgyous for a knock-out allele exhibit pericardial effusion, growth restriction, absent right ventricle, single left-sided ventricle and embryonic lethality.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    696
  • Tissues
    46
  • cDNA Data
    10
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      131
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 102636514 NCBI Gene Model | MGI Sequence Detail 16599 C57BL/6J ±  kb
    transcript NR_154048 RefSeq | MGI Sequence Detail 806 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 10
      Primer pair 7
      Other 2

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2142734, MGI:5904339
    References
    more
    • Summaries
      All 19
      Developmental Gene Expression 5
      Phenotypes 5
    • Earliest
      J:155956 Feng W, et al., Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS One. 2009;4(12):e8066
    • Latest
      J:345311 Ferguson CA, et al., Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs. Dev Dyn. 2024 Feb;253(2):215-232
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory