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Paupar Gene Detail
Summary
  • Symbol
    Paupar
  • Name
    Pax6 upstream antisense RNA
Location &
Maps
more
  • Sequence Map
    Chr2:105488207-105491688 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    115 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5543919
 lncRNA gene Chr2:105488207-105491688 (-)
129S1/SvImJ ENSMUSG00200008122
 lncRNA gene Chr2:102312125-102315583 (-)
A/J ENSMUSG00195032140
 lncRNA gene Chr2:102473464-102476929 (-)
AKR/J ENSMUSG00220005076
 lncRNA gene Chr2:102218890-102222355 (-)
BALB/cJ ENSMUSG00180033723
 lncRNA gene Chr2:102268893-102272358 (-)
C3H/HeJ ENSMUSG00175033323
 lncRNA gene Chr2:102567985-102571430 (-)
C57BL/6NJ ENSMUSG00215026123
 lncRNA gene Chr2:102375253-102378734 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0005443
 lincRNA gene Chr2:99124813-99127680 (-)
CAST/EiJ ENSTCUG00005005947
 lncRNA gene Chr2:101629185-101632607 (-)
CBA/J ENSMUSG00210040192
 lncRNA gene Chr2:102546566-102550029 (-)
DBA/2J ENSMUSG00185040335
 lncRNA gene Chr2:102265490-102268953 (-)
FVB/NJ ENSMUSG00205018921
 lncRNA gene Chr2:101604866-101608337 (-)
JF1/MsJ ENSUMUG00000003990
 lncRNA gene Chr2:101977597-101981042 (-)
LP/J ENSMUSG00230006537
 lncRNA gene Chr2:104014798-104018261 (-)
NOD/ShiLtJ ENSMUSG00190016481
 lncRNA gene Chr2:102393400-102396860 (-)
NZO/HlLtJ ENSMUSG00225008771
 lncRNA gene Chr2:111923648-111927125 (-)
PWK/PhJ ENSLUMG00010024680
 lncRNA gene Chr2:101980576-101984025 (-)
SPRET/EiJ ENSMSPG00010039113
 lncRNA gene Chr2:104023493-104026983 (-)
WSB/EiJ ENSIUOG00005032266
 lncRNA gene Chr2:102068143-102071611 (-)



Homology
more
  • Human Ortholog
    PAUPAR, PAX6 upstream antisense RNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAUPAR, PAX6 upstream antisense RNA
  • Links
    NCBI Gene ID: 103157000

  • Chr Location
    11p13; chr11:31812307-32002405 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display dysregulation of pancreatic alpha cells with defects in glucagon secretion and glucose homeostasis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      25
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 103164605 NCBI Gene Model | MGI Sequence Detail 3482 C57BL/6J ±  kb
    transcript NR_117095 RefSeq | MGI Sequence Detail 3482 Not Specified  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1
    References
    more
    • Summaries
      All 12
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:282894 Singer RA, et al., The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019 Dec 3;30(6):1091-1106.e8
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory