Mir195b Gene Detail

Summary

• Symbol
  Mir195b
• Name
  microRNA 195b
• Synonyms
  mmu-mir-195b

• Feature Type
  miRNA gene
• IDs
  MGI:5530873
  NCBI Gene: 102465169
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr2:56675823-56675919 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  119 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5530873	miRNA gene	Chr2:56675823-56675919 (+)
129S1/SvImJ	ENSMUSG00200003085	miRNA gene	Chr2:53728050-53728146 (+)
A/J	ENSMUSG00195005296	miRNA gene	Chr2:53853001-53853097 (+)
AKR/J	ENSMUSG00220007439	miRNA gene	Chr2:53941805-53941901 (+)
BALB/cJ	ENSMUSG00180020613	miRNA gene	Chr2:53813536-53813632 (+)
C3H/HeJ	ENSMUSG00175014271	miRNA gene	Chr2:53878067-53878163 (+)
C57BL/6NJ	ENSMUSG00215008610	miRNA gene	Chr2:53847129-53847225 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007717	miRNA gene	Chr2:51766955-51767051 (+)
CAST/EiJ	ENSTCUG00005022948	miRNA gene	Chr2:53226575-53226671 (+)
CBA/J	ENSMUSG00210035143	miRNA gene	Chr2:53897656-53897752 (+)
DBA/2J	ENSMUSG00185008725	miRNA gene	Chr2:53753544-53753640 (+)
FVB/NJ	ENSMUSG00205021527	miRNA gene	Chr2:53384363-53384459 (+)
JF1/MsJ	ENSUMUG00000024654	miRNA gene	Chr2:53471216-53471310 (+)
LP/J	ENSMUSG00230001946	miRNA gene	Chr2:55620498-55620594 (+)
NOD/ShiLtJ	ENSMUSG00190045323	miRNA gene	Chr2:53835461-53835557 (+)
NZO/HlLtJ	ENSMUSG00225001231	miRNA gene	Chr2:63318883-63318979 (+)
PWK/PhJ	ENSLUMG00010005529	miRNA gene	Chr2:53625893-53625989 (+)
SPRET/EiJ	ENSMSPG00010011907	miRNA gene	Chr2:54688852-54688948 (+)
WSB/EiJ	ENSIUOG00005028475	miRNA gene	Chr2:53818355-53818451 (+)

Homology

• Gene Tree
  Mir195b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Mir195b
• Find Mice (IMSR)
  0 strains or lines available

Homozygous null mice show no gross anatomical defects but aged mice have altered cell cycle regulation, metabolism, and oxidative stress markers in heart, liver, and lungs.

Expression

• Assay Results
  597
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  23
• RefSeq
  1

• Ensembl
  ENSMUSG00000098437 (Evidence)
• NCBI Gene
  102465169

Representative Sequences			Length	Strain/Species
genomic	102465169	NCBI Gene Model | MGI Sequence Detail	97	C57BL/6J
transcript	NR_105751	RefSeq | MGI Sequence Detail	97	ZRU/MplStud

Other Database
Links

miRBase

MI0021861

References

• Summaries
  All 10

  Developmental Gene Expression 1

  Phenotypes 3
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:344186 Munoz-Gallardo MDM, et al., miR-195b is required for proper cellular homeostasis in the elderly. Sci Rep. 2024 Jan 8;14(1):810