Lhx5as1 Gene Detail

Summary

• Symbol
  Lhx5as1
• Name
  LIM homeobox 5, antisense 1
• Synonyms
  Gm27199

• Feature Type
  lncRNA gene
• IDs
  MGI:5521042
  NCBI Gene: 102634302
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr5:120557721-120569832 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  348 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5521042	lncRNA gene	Chr5:120557719-120569865 (-)
129S1/SvImJ	ENSMUSG00200030334	lncRNA gene	Chr5:114296908-114309033 (-)
A/J	ENSMUSG00195013056	lncRNA gene	Chr5:113818013-113830143 (-)
AKR/J	ENSMUSG00220046237	lncRNA gene	Chr5:113318784-113330918 (-)
BALB/cJ	ENSMUSG00180038316	lncRNA gene	Chr5:113932609-113944733 (-)
C3H/HeJ	ENSMUSG00175030791	lncRNA gene	Chr5:115930724-115942833 (-)
C57BL/6NJ	ENSMUSG00215043331	lncRNA gene	Chr5:113964520-113976654 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003753	antisense lncRNA gene	Chr5:113371910-113383803 (-)
CAST/EiJ	ENSTCUG00005042405	lncRNA gene	Chr5:113137939-113150142 (-)
CBA/J	ENSMUSG00210010428	lncRNA gene	Chr5:114681618-114693729 (-)
DBA/2J	ENSMUSG00185054098	lncRNA gene	Chr5:117740926-117753041 (-)
FVB/NJ	ENSMUSG00205045253	lncRNA gene	Chr5:113594705-113606847 (-)
JF1/MsJ	ENSUMUG00000054487	lncRNA gene	Chr5:120577115-120589355 (-)
LP/J	ENSMUSG00230047413	lncRNA gene	Chr5:121819123-121831252 (-)
NOD/ShiLtJ	ENSMUSG00190043669	lncRNA gene	Chr5:113628833-113640959 (-)
NZO/HlLtJ	ENSMUSG00225018202	lncRNA gene	Chr5:129496287-129508409 (-)
PWK/PhJ	ENSLUMG00010046542	lncRNA gene	Chr5:112477637-112489773 (-)
SPRET/EiJ	ENSMSPG00010046416	lncRNA gene	Chr5:115795430-115807638 (-)
WSB/EiJ	ENSIUOG00005019150	lncRNA gene	Chr5:116319954-116332010 (-)

Homology

• Gene Tree
  Lhx5as1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Lhx5as1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele display decreased excitatory postsynaptic and miniature excitatory postsynaptic current amplitudes and impaired spatial learning and memory.

Expression

• Assay Results
  598
• Tissues
  1
• cDNA Data
  1
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  55
• RefSeq
  1

• Ensembl
  ENSMUSG00000098649 (Evidence)
• NCBI Gene
  102634302

Representative Sequences			Length	Strain/Species
genomic	102634302	NCBI Gene Model | MGI Sequence Detail	12112	C57BL/6J
transcript	NR_166585	RefSeq | MGI Sequence Detail	626	C57BL/6

Molecular
Reagents

• All nucleic 2

  cDNA 1

  Primer pair 1

Other
Accession IDs

MGI:5591135, MGI:7526333

References

• Summaries
  All 16

  Developmental Gene Expression 2

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:338207 Moreau MX, et al., Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons. Dev Cell. 2023 Jun 7;

TSS for Lhx5as1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr52923	Chr5:120569822-120569836 (-)	3 bp