Lbhd1 Gene Detail

Summary

• Symbol
  Lbhd1
• Name
  LBH domain containing 1
• Synonyms
  Gm21743

• Feature Type
  protein coding gene
• IDs
  MGI:5516029
  NCBI Gene: 102308570
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr19:8861242-8868123 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  40 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5516029	protein coding gene	Chr19:8861096-8869991 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024818	protein coding gene	Chr19:6168005-6177796 (+)
A/J	MGP_AJ_G0024786	protein coding gene	Chr19:5835639-5844465 (+)
AKR/J	MGP_AKRJ_G0024761	protein coding gene	Chr19:5931592-5941303 (+)
BALB/cJ	MGP_BALBcJ_G0024786	protein coding gene	Chr19:5942657-5951563 (+)
C3H/HeJ	MGP_C3HHeJ_G0024552	protein coding gene	Chr19:6017536-6026683 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025233	protein coding gene	Chr19:6304410-6313302 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022662	protein coding gene	Chr19:6089693-6099080 (+)
CAST/EiJ	MGP_CASTEiJ_G0024025	protein coding gene	Chr19:5669074-5679918 (+)
CBA/J	MGP_CBAJ_G0024526	protein coding gene	Chr19:6414004-6424914 (+)
DBA/2J	MGP_DBA2J_G0024653	protein coding gene	Chr19:5668275-5677296 (+)
FVB/NJ	MGP_FVBNJ_G0024620	protein coding gene	Chr19:5741001-5750109 (+)
LP/J	MGP_LPJ_G0024740	protein coding gene	Chr19:6063025-6072821 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024647	protein coding gene	Chr19:6278157-6289489 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025282	protein coding gene	Chr19:5976550-5986306 (+)
PWK/PhJ	MGP_PWKPhJ_G0023770	protein coding gene	Chr19:5342458-5351927 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023575	protein coding gene	Chr19:5584877-5593747 (+)
WSB/EiJ	MGP_WSBEiJ_G0024087	protein coding gene	Chr19:5948848-5957828 (+)

Homology

• Human Ortholog
  LBHD1, LBH domain containing 1

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  LBHD1, LBH domain containing 1
  
• Synonyms
  C11orf48
• Links
  HGNC:28351

  NCBI Gene ID: 79081

  neXtProt AC: NX_Q9BQE6

  UniProt: Q9BQE6

  
  
• Chr Location
  11q12.3; chr11:62662817-62672267 (-)  GRCh38

---

• MGI Vertebrate Homology
  Lbhd1 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: LBHD1
• Gene Tree
  Lbhd1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  12
• Gene trapped
  12
• Find Mice (IMSR)
  7 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase lbhd1

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS79682.1

• Ensembl
  ENSMUSG00000096740 (Evidence)
• NCBI Gene
  102308570

Representative Sequences			Length	Strain/Species
genomic	102308570	NCBI Gene Model | MGI Sequence Detail	6882	C57BL/6J
transcript	NM_001286103	RefSeq | MGI Sequence Detail	1150	ZRU/MplStud
polypeptide	NP_001273032	RefSeq | MGI Sequence Detail	259	ZRU/MplStud

Protein
Information

• UniProt
  1 Sequence
• EC
  102308570
• InterPro Domains
  IPR038990 LBH domain
  IPR042945 LBH domain containing protein

Molecular
Reagents

• All nucleic 1

  cDNA 1

Other
Accession IDs

MGI:5433907

References

• Summaries
  All 10

  Phenotypes 3
• Earliest
  J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
• Latest
  J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

TSS for Lbhd1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr154869	Chr19:8861212-8861225 (+)	-23 bp
Tssr154870	Chr19:8861229-8861273 (+)	9 bp
Tssr154871	Chr19:8861274-8861292 (+)	41 bp