Gm20521 Gene Detail

Summary

• Symbol
  Gm20521
• Name
  predicted gene 20521

• Feature Type
  protein coding gene
• IDs
  MGI:5141986
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr14:55120898-55135594 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.98 cM

Strain
Comparison

• SNPs within 2kb
  102 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5141986	protein coding gene	Chr14:55120898-55135594 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021328	protein coding gene	Chr14:48865433-48880147 (+)
A/J	MGP_AJ_G0021287	protein coding gene	Chr14:47900364-47916368 (+)
AKR/J	MGP_AKRJ_G0021263	protein coding gene	Chr14:49646770-49661427 (+)
BALB/cJ	MGP_BALBcJ_G0021291	protein coding gene	Chr14:47879042-47893757 (+)
C3H/HeJ	MGP_C3HHeJ_G0021071	protein coding gene	Chr14:49339076-49353744 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021729	protein coding gene	Chr14:51330337-51351849 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019276	protein coding gene	Chr14:46313704-46328550 (+)
CAST/EiJ	MGP_CASTEiJ_G0020590	protein coding gene	Chr14:45576619-45592500 (+)
CBA/J	MGP_CBAJ_G0021038	protein coding gene	Chr14:52895719-52910382 (+)
DBA/2J	MGP_DBA2J_G0021159	protein coding gene	Chr14:47642455-47657179 (+)
FVB/NJ	MGP_FVBNJ_G0021141	protein coding gene	Chr14:47099926-47114751 (+)
LP/J	MGP_LPJ_G0021233	protein coding gene	Chr14:49885397-49900528 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021165	protein coding gene	Chr14:52278136-52294344 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021756	protein coding gene	Chr14:48823160-48838846 (+)
PWK/PhJ	MGP_PWKPhJ_G0020337	protein coding gene	Chr14:44177474-44192345 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020165	protein coding gene	Chr14:44807191-44821830 (+)
WSB/EiJ	MGP_WSBEiJ_G0020643	protein coding gene	Chr14:49116184-49130914 (+)

Homology

• Gene Tree
  Gm20521
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (other)
  1
• Genomic Mutations
  1 involving Gm20521
• Find Mice (IMSR)
  2 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Interactions

• Gm20521 interacts with 10 markers (Mir129-1, Mir129-2, Mir130a, ...) View All

Sequences &
Gene Models

• All Sequences
  22
• UniProt
  1

• Ensembl
  ENSMUSG00000092232 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000092232	Ensembl Gene Model | MGI Sequence Detail	14697	C57BL/6J
transcript	ENSMUST00000134077	Ensembl | MGI Sequence Detail	1245	Not Applicable
polypeptide	ENSMUSP00000117229	Ensembl | MGI Sequence Detail	333	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR020717 Apoptosis regulator, Bcl-2, BH1 motif, conserved site
  IPR020731 Apoptosis regulator, Bcl-2, BH4 motif, conserved site
  IPR003093 Apoptosis regulator, Bcl-2 protein, BH4
  IPR013280 Apoptosis regulator, Bcl-W
  IPR046371 Bcl-2, Bcl-2 homology region 1-3
  IPR026298 Bcl-2 family
  IPR002475 Bcl2-like
  IPR036834 Bcl-2-like superfamily
  IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
  IPR035979 RNA-binding domain superfamily
  IPR000504 RNA recognition motif domain

References

• Summaries
  All 5

  Phenotypes 2
• Earliest
  J:23389 Roderick TH, Using inversions to detect and study recessive lethals and detrimentals in mice, in Utilization of Mammalian Specific Locus Studies in Hazard Evaluation and Estimation of Genetic Risk. 1983:135-67.
• Latest
  J:109762 Mouse Genome Informatics and VEGA Genome Database Project, Collaboration to Associate VEGA (Vertebrate Genome Annotation) Mouse Gene Models with MGI Markers. Database Release. 2006;

TSS for Gm20521:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125672	Chr14:55120887-55120946 (+)	19 bp
Tssr125673	Chr14:55121027-55121051 (+)	141 bp
Tssr125674	Chr14:55128977-55128981 (+)	8,081 bp