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Mroh6 Gene Detail
Summary
  • Symbol
    Mroh6
  • Name
    maestro heat-like repeat family member 6
  • Synonyms
    Gm19570
  • Feature Type
    protein coding gene
  • IDs
    MGI:5011755
    NCBI Gene: 223645
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75755986-75760619 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5011755
 protein coding gene Chr15:75753085-75762544 (-)
129S1/SvImJ ENSMUSG00200050774
 protein coding gene Chr15:72873486-72878120 (-)
A/J ENSMUSG00195048014
 protein coding gene Chr15:72847887-72852520 (-)
AKR/J ENSMUSG00220047113
 protein coding gene Chr15:72858951-72863585 (-)
BALB/cJ ENSMUSG00180049853
 protein coding gene Chr15:72674618-72679251 (-)
C3H/HeJ ENSMUSG00175050976
 protein coding gene Chr15:73036504-73041137 (-)
C57BL/6NJ ENSMUSG00215046878
 protein coding gene Chr15:72765038-72769673 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019899
 protein coding gene Chr15:69838431-69843009 (-)
CAST/EiJ ENSTCUG00005044298
 protein coding gene Chr15:72377813-72382440 (-)
CBA/J ENSMUSG00210038565
 protein coding gene Chr15:72811788-72816422 (-)
DBA/2J ENSMUSG00185050262
 protein coding gene Chr15:72790482-72795115 (-)
FVB/NJ ENSMUSG00205026108
 protein coding gene Chr15:72541191-72545824 (-)
JF1/MsJ ENSUMUG00000054500
 protein coding gene Chr15:72445323-72449949 (-)
LP/J ENSMUSG00230051135
 protein coding gene Chr15:76154476-76159109 (-)
NOD/ShiLtJ ENSMUSG00190039930
 protein coding gene Chr15:72794170-72798801 (-)
NZO/HlLtJ ENSMUSG00225049007
 protein coding gene Chr15:76459005-76463636 (-)
PWK/PhJ ENSLUMG00010050008
 protein coding gene Chr15:72726304-72730931 (-)
SPRET/EiJ ENSMSPG00010040130
 protein coding gene Chr15:74351230-74355831 (-)
WSB/EiJ ENSIUOG00005036458
 protein coding gene Chr15:72851361-72855992 (-)



Homology
more
  • Human Ortholog
    MROH6, maestro heat like repeat family member 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MROH6, maestro heat like repeat family member 6
  • Synonyms
    C8orf73
  • Links
    NCBI Gene ID: 642475
    UniProt: A6NGR9

  • Chr Location
    8q24.3; chr8:143566192-143572772 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    3
  • Gene trapped
    3
  • Radiation induced
    2
  • Genomic Mutations
    5 involving Mroh6
  • Find Mice (IMSR)
    16 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000098678 Ensembl Gene Model | MGI Sequence Detail 4634 C57BL/6J ±  kb
transcript ENSMUST00000184858 Ensembl | MGI Sequence Detail 2216 Not Applicable  
polypeptide ENSMUSP00000139029 Ensembl | MGI Sequence Detail 722 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR011989 Armadillo-like helical
    IPR016024 Armadillo-type fold
    IPR045206 Maestro heat-like repeat-containing protein
    IPR048465 Maestro-like, HEAT-repeats domain
    IPR055406 Maestro/Maestro-like, HEAT-repeats domain
  • GlyGen
    V9GX81 1 site
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 39
    Diseases 1
    Gene Ontology 1
    Phenotypes 29
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory