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Mir378b Gene Detail
Summary
  • Symbol
    Mir378b
  • Name
    microRNA 378b
  • Synonyms
    mmu-mir-378b
Location &
Maps
more
  • Sequence Map
    Chr11:88243599-88243690 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 52.40 cM
Strain
Comparison
more
  • SNPs within 2kb
    53 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4950393
miRNA gene Chr11:88243599-88243690 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007860
miRNA gene Chr11:90070824-90070915 (+)
A/J MGP_AJ_G0007853
miRNA gene Chr11:86572856-86572947 (+)
AKR/J MGP_AKRJ_G0007828
miRNA gene Chr11:89202904-89202995 (+)
BALB/cJ MGP_BALBcJ_G0007832
miRNA gene Chr11:86987145-86987236 (+)
C3H/HeJ MGP_C3HHeJ_G0007778
miRNA gene Chr11:89233284-89233375 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008011
miRNA gene Chr11:92812763-92812854 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007152
miRNA gene Chr11:83590433-83590524 (+)
CAST/EiJ MGP_CASTEiJ_G0007672
miRNA gene Chr11:89913640-89913731 (+)
CBA/J MGP_CBAJ_G0007749
miRNA gene Chr11:96740527-96740618 (+)
DBA/2J MGP_DBA2J_G0007784
miRNA gene Chr11:86130788-86130879 (+)
FVB/NJ MGP_FVBNJ_G0007803
miRNA gene Chr11:85634931-85635022 (+)
LP/J MGP_LPJ_G0007862
miRNA gene Chr11:90587435-90587526 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007773
miRNA gene Chr11:96735956-96736047 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008007
miRNA gene Chr11:89420141-89420232 (+)
PWK/PhJ MGP_PWKPhJ_G0007599
miRNA gene Chr11:86972626-86972717 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007494
miRNA gene Chr11:89009877-89009968 (+)
WSB/EiJ MGP_WSBEiJ_G0007739
miRNA gene Chr11:89314519-89314610 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females with a null allele are unable to clear Chlamydia infection and have higher bacterial burden during infection, however mice show reduced uterine pathology, protection from Chlamydia-induced infertility, and reduced proinflammatory immune response following infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100628571 NCBI Gene Model | MGI Sequence Detail 92 C57BL/6J ±  kb
    transcript NR_039545 RefSeq | MGI Sequence Detail 92 ZRU/MplStud  
    For the selected sequence
    Other Database
    Links
    less
    miRBase MI0016973
    References
    more
    • Summaries
      All 15
      Diseases 1
      Gene Ontology 1
      Phenotypes 10
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:307588 Lundy SR, et al., MiR-378b Modulates Chlamydia-Induced Upper Genital Tract Pathology. Pathogens. 2021 May 7;10(5)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory