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Esp8 Gene Detail
Summary
  • Symbol
    Esp8
  • Name
    exocrine gland secreted peptide 8
  • Synonyms
    Gm17495
Location &
Maps
more
  • Sequence Map
    Chr17:40830913-40841312 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    441 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4937129
 protein coding gene Chr17:40830913-40841593 (+)
129S1/SvImJ ENSMUSG00200051215
 protein coding gene Chr17:35983978-35994323 (+)
A/J ENSMUSG00195041296
 protein coding gene Chr17:37496035-37506441 (+)
AKR/J ENSMUSG00220036240
 protein coding gene Chr17:36498398-36508755 (+)
BALB/cJ ENSMUSG00180041927
 protein coding gene Chr17:37294377-37304789 (+)
C3H/HeJ ENSMUSG00175035237
 protein coding gene Chr17:36577463-36587820 (+)
C57BL/6NJ ENSMUSG00215052986
 protein coding gene Chr17:36115995-36126394 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005050241
 protein coding gene Chr17:37312119-37322477 (+)
CBA/J ENSMUSG00210047399
 protein coding gene Chr17:36315352-36325709 (+)
DBA/2J ENSMUSG00185051662
 protein coding gene Chr17:39275244-39285659 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000031006
 protein coding gene Chr17:38922178-38932592 (+)
LP/J ENSMUSG00230054479
 protein coding gene Chr17:40094138-40104483 (+)
NOD/ShiLtJ ENSMUSG00190029293
 protein coding gene Chr17:36163836-36174241 (+)
NZO/HlLtJ ENSMUSG00225042245
 protein coding gene Chr17:42363500-42373905 (+)
PWK/PhJ ENSLUMG00010039984
 protein coding gene Chr17:36141890-36152304 (+)
SPRET/EiJ ENSMSPG00010042846
 protein coding gene Chr17:36479867-36491416 (+)
WSB/EiJ ENSIUOG00005049528
 protein coding gene Chr17:37143491-37153839 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    601
  • Tissues
    2
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090747 Ensembl Gene Model | MGI Sequence Detail 10400 C57BL/6J ±  kb
transcript ENSMUST00000171813 Ensembl | MGI Sequence Detail 620 Not Applicable  
polypeptide ENSMUSP00000129933 Ensembl | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR032253 Exocrine gland-secreted peptide Esp1/Esp22
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Primer pair 1
References
more
  • Summaries
    All 15
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:174752 Kimoto H, et al., Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Curr Biol. 2007 Nov 6;17(21):1879-84
  • Latest
    J:279933 Zhang X, et al., Loss-of-function mutations in FREM2 disrupt eye morphogenesis. Exp Eye Res. 2019 Apr;181:302-312
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory