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Esp8 Gene Detail
Summary
  • Symbol
    Esp8
  • Name
    exocrine gland secreted peptide 8
  • Synonyms
    Gm17495
  • Feature Type
    protein coding gene
  • IDs
    MGI:4937129
    NCBI Gene: 100126778
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:40830913-40841312 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4937129
 protein coding gene Chr17:40830913-40841593 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023754
 protein coding gene Chr17:41336324-41346826 (+)
A/J MGP_AJ_G0023712
 protein coding gene Chr17:40396739-40406168 (+)
AKR/J MGP_AKRJ_G0023684
 protein coding gene Chr17:40541169-40554748 (+)
BALB/cJ MGP_BALBcJ_G0023716
 protein coding gene Chr17:40265875-40278674 (+)
C3H/HeJ MGP_C3HHeJ_G0023481
 protein coding gene Chr17:41227302-41238112 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024158
 protein coding gene Chr17:43181007-43191195 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022962
 protein coding gene Chr17:41252724-41265744 (+)
CBA/J MGP_CBAJ_G0023457
 protein coding gene Chr17:44667563-44678029 (+)
DBA/2J MGP_DBA2J_G0023582
 protein coding gene Chr17:39196940-39209022 (+)
FVB/NJ MGP_FVBNJ_G0023549
 protein coding gene Chr17:38820873-38830702 (+)
LP/J MGP_LPJ_G0023663
 protein coding gene Chr17:41957851-41966911 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023578
 protein coding gene Chr17:44107724-44130450 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024204
 protein coding gene Chr17:40875130-40883334 (+)
PWK/PhJ MGP_PWKPhJ_G0022706
 protein coding gene Chr17:38558923-38570028 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022524
 protein coding gene Chr17:38027217-38036647 (+)
WSB/EiJ MGP_WSBEiJ_G0023027
 protein coding gene Chr17:41431465-41440837 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090747 Ensembl Gene Model | MGI Sequence Detail 10400 C57BL/6J ±  kb
transcript ENSMUST00000171813 Ensembl | MGI Sequence Detail 620 Not Applicable  
polypeptide ENSMUSP00000129933 Ensembl | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR032253 Exocrine gland-secreted peptide Esp1/Esp22
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Primer pair 1
References
more
  • Summaries
    All 12
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:174752 Kimoto H, et al., Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Curr Biol. 2007 Nov 6;17(21):1879-84
  • Latest
    J:279933 Zhang X, et al., Loss-of-function mutations in FREM2 disrupt eye morphogenesis. Exp Eye Res. 2019 Apr;181:302-312
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory