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Trim12c Gene Detail
Summary
  • Symbol
    Trim12c
  • Name
    tripartite motif-containing 12C
  • Synonyms
    9230105E10Rik, Trim12-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:4821183
    NCBI Gene: 319236
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:103987961-104002569 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    741 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4821183
 protein coding gene Chr7:103987961-104002649 (-)
129S1/SvImJ ENSMUSG00200044119
 protein coding gene Chr7:90754175-90781591 (-)
A/J ENSMUSG00195054256
 protein coding gene Chr7:95269538-95284158 (-)
AKR/J ENSMUSG00220046474
 protein coding gene Chr7:88643552-88658189 (-)
BALB/cJ ENSMUSG00180041181
 protein coding gene Chr7:91936262-91963696 (-)
C3H/HeJ ENSMUSG00175051415
 protein coding gene Chr7:92579355-92606777 (-)
C57BL/6NJ ENSMUSG00215048327
 protein coding gene Chr7:91836158-91850862 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030187
 protein coding gene Chr7:106765939-106780265 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210046581
 protein coding gene Chr7:92417701-92432303 (-)
DBA/2J ENSMUSG00185056601
 protein coding gene Chr7:96770063-96784670 (-)
FVB/NJ ENSMUSG00205043398
 protein coding gene Chr7:92403765-92418372 (-)
JF1/MsJ ENSUMUG00000035373
 protein coding gene Chr7:101829972-101845897 (-)
LP/J ENSMUSG00230041420
 protein coding gene Chr7:102871826-102886429 (-)
NOD/ShiLtJ ENSMUSG00190037486
 protein coding gene Chr7:92698202-92712824 (-)
NZO/HlLtJ ENSMUSG00225016198
 protein coding gene Chr7:101066466-101084053 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005049036
 protein coding gene Chr7:93004538-93022125 (-)



Homology
more
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Synonyms
    RNF88, TRIM5alpha
  • Links
    NCBI Gene ID: 85363
    UniProt: Q9C035

  • Chr Location
    11p15.4; chr11:5588635-5938619 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    620
  • Tissues
    14
  • cDNA Data
    33
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057143 Ensembl Gene Model | MGI Sequence Detail 14609 C57BL/6J ±  kb
transcript ENSMUST00000059037 Ensembl | MGI Sequence Detail 3740 Not Applicable  
polypeptide ENSMUSP00000060100 Ensembl | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 33
    cDNA 33

    Microarray probesets 3
Other
Accession IDs
less
MGI:2441735
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:349812 Schafer A, et al., Mapping of susceptibility loci for Ebola virus pathogenesis in mice. Cell Rep. 2024 May 28;43(5):114127
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory