Parail Gene Detail

Summary

• Symbol
  Parail
• Name
  palmitic acid regulated anti-inflammatory lncRNA
• Synonyms
  A530072M11Rik

• Feature Type
  lncRNA gene
• IDs
  MGI:4440477
  NCBI Gene: 100415915
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr4:16164110-16266225 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 6.71 cM

Strain
Comparison

• SNPs within 2kb
  2943 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4440477	lncRNA gene	Chr4:16162974-16266227 (+)
129S1/SvImJ	ENSMUSG00200001182	lncRNA gene	Chr4:12848547-12952570 (+)
A/J	ENSMUSG00195017091	lncRNA gene	Chr4:13296167-13398257 (+)
AKR/J	ENSMUSG00220001286	lncRNA gene	Chr4:13035952-13139987 (+)
BALB/cJ	ENSMUSG00180001906	lncRNA gene	Chr4:12796866-12900895 (+)
C3H/HeJ	ENSMUSG00175018453	lncRNA gene	Chr4:13279360-13381502 (+)
C57BL/6NJ	ENSMUSG00215010797	lncRNA gene	Chr4:12916290-13018461 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013662	unclassified non-coding RNA gene	Chr4:11891479-11988201 (+)
CAST/EiJ	ENSTCUG00005016554	lncRNA gene	Chr4:12951829-13057481 (+)
CBA/J	ENSMUSG00210001655	lncRNA gene	Chr4:13017530-13119671 (+)
DBA/2J	ENSMUSG00185001268	lncRNA gene	Chr4:13127824-13229971 (+)
FVB/NJ	ENSMUSG00205002008	lncRNA gene	Chr4:12675685-12777849 (+)
JF1/MsJ	ENSUMUG00000001896	lncRNA gene	Chr4:13179139-13287077 (+)
LP/J	ENSMUSG00230001236	lncRNA gene	Chr4:16345980-16450004 (+)
NOD/ShiLtJ	ENSMUSG00190026132	lncRNA gene	Chr4:12959796-13061944 (+)
NZO/HlLtJ	ENSMUSG00225001882	lncRNA gene	Chr4:20309023-20411168 (+)
PWK/PhJ	ENSLUMG00010001859	lncRNA gene	Chr4:12643608-12743646 (+)
SPRET/EiJ	ENSMSPG00010013292	lncRNA gene	Chr4:13138949-13239680 (+)
WSB/EiJ	ENSIUOG00005008337	lncRNA gene	Chr4:12686834-12789211 (+)

Homology

• Human Ortholog
  PARAIL, palmitic acid regulated anti-inflammatory lncRNA

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PARAIL, palmitic acid regulated anti-inflammatory lncRNA
  
• Synonyms
  RIPK2-DT
• Links
  HGNC:55545

  NCBI Gene ID: 101929709

  
  
• Chr Location
  chr8:89545423-89902429 (-)  GRCh38

---

• MGI Vertebrate Homology
  Parail stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: PARAIL
• Gene Tree
  Parail
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Gene trapped
  1
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  1

• Ensembl
  ENSMUSG00000085112 (Evidence)
• NCBI Gene
  100415915

Representative Sequences			Length	Strain/Species
genomic	100415915	NCBI Gene Model | MGI Sequence Detail	102116	C57BL/6J
transcript	NR_045765	RefSeq | MGI Sequence Detail	1852	C57BL/6

Molecular
Reagents

• All nucleic 2

  cDNA 2

Other
Accession IDs

MGI:8169653

References

• Summaries
  All 9

  Phenotypes 2
• Earliest
  J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
• Latest
  J:362667 Tanwar VS, et al., Palmitic Acid-Induced Long Noncoding RNA PARAIL Regulates Inflammation via Interaction With RNA-Binding Protein ELAVL1 in Monocytes and Macrophages. Arterioscler Thromb Vasc Biol. 2023 Jul;43(7):1157-1175