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Ighv1-22 Gene Detail
Summary
  • Symbol
    Ighv1-22
  • Name
    immunoglobulin heavy variable 1-22
  • Synonyms
    Gm16860
Location &
Maps
more
  • Sequence Map
    Chr12:114709893-114710186 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    184 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439784
 gene segment Chr12:114709893-114710326 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J ENSMUSG00220043034
 gene segment Chr12:106887344-106887776 (-)
BALB/cJ ENSMUSG00180051972
 gene segment Chr12:108996633-108997066 (-)
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215050091
 gene segment Chr12:107499795-107500228 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005044984
 gene segment Chr12:107620931-107621358 (-)
CAST/EiJ ENSTCUG00005043022
 gene segment Chr12:108079653-108080086 (-)
CAST/EiJ ENSTCUG00005045016
 gene segment Chr12:108073759-108074192 (-)
CAST/EiJ ENSTCUG00005043017
 gene segment Chr12:107571992-107572425 (-)
CBA/J ENSMUSG00210039028
 gene segment Chr12:107954501-107954933 (-)
DBA/2J ENSMUSG00185033085
 gene segment Chr12:109866758-109867191 (-)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000031709
 gene segment Chr12:114514369-114514802 (-)
LP/J ENSMUSG00230049227
 gene segment Chr12:116762445-116762878 (-)
NOD/ShiLtJ ENSMUSG00190041918
 gene segment Chr12:106345604-106346037 (-)
NZO/HlLtJ ENSMUSG00225043679
 gene segment Chr12:118689911-118690343 (-)
PWK/PhJ ENSLUMG00010051899
 gene segment Chr12:108251510-108251943 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005038306
 gene segment Chr12:107343474-107343907 (-)



Homology
more
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Vertebrate Orthologs
    17
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Synonyms
    IGHV118
  • Links
    NCBI Gene ID: 28468
    UniProt: A0A0C4DH31

  • Chr Location
    14q32.33; chr14:106184899-106185394 (-)  GRCh38
  • Human Ortholog
    IGHV1-2, immunoglobulin heavy variable 1-2
  • Synonyms
    IGHV12, V35
  • Links
    NCBI Gene ID: 28474

  • Chr Location
    14q32.33; chr14:105986582-105987083 (-)  GRCh38
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38
  • Human Ortholog
    IGHV1-3, immunoglobulin heavy variable 1-3
  • Synonyms
    IGHV13, VI-3B
  • Links
    NCBI Gene ID: 28473
    UniProt: A0A0C4DH29

  • Chr Location
    14q32.33; chr14:106005095-106005574 (-)  GRCh38
  • Human Ortholog
    IGHV1-38-4, immunoglobulin heavy variable 1-38-4 (non-functional)
  • Synonyms
    IGHV1-C, IGHV1C
  • Links
    NCBI Gene ID: 28460
    UniProt: P0DTW3

  • Chr Location
    14q32.33
  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Synonyms
    IGHV145, VH
  • Links
    NCBI Gene ID: 28466
    UniProt: A0A0A0MS14

  • Chr Location
    14q32.33; chr14:106506996-106507491 (-)  GRCh38
  • Human Ortholog
    IGHV1-46, immunoglobulin heavy variable 1-46
  • Synonyms
    IGHV146
  • Links
    NCBI Gene ID: 28465

  • Chr Location
    14q32.33; chr14:106511115-106511856 (-)  GRCh38
  • Human Ortholog
    IGHV1-58, immunoglobulin heavy variable 1-58
  • Synonyms
    IGHV158, VH
  • Links
    NCBI Gene ID: 28464
    UniProt: A0A0C4DH39

  • Chr Location
    14q32.33; chr14:106622357-106622855 (-)  GRCh38
  • Human Ortholog
    IGHV1-69, immunoglobulin heavy variable 1-69
  • Synonyms
    IGHV169, IGHV1-E, IGHV1E
  • Links
    NCBI Gene ID: 28461
    UniProt: P01742

  • Chr Location
    14q32.33; chr14:106714682-106715181 (-)  GRCh38
  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1-F, IGHV1F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38
  • Human Ortholog
    IGHV1-69D, immunoglobulin heavy variable 1-69D
  • Links
    NCBI Gene ID: 102723169
    UniProt: A0A0B4J2H0

  • Chr Location
    14q32.33; chr14:106762092-106762588 (-)  GRCh38
  • Human Ortholog
    IGHV1-8, immunoglobulin heavy variable 1-8
  • Synonyms
    IGHV18
  • Links
    NCBI Gene ID: 28472
    UniProt: P0DP01

  • Chr Location
    14q32.33
  • Human Ortholog
    IGHV1OR15-1, immunoglobulin heavy variable 1/OR15-1 (non-functional)
  • Synonyms
    IGHV1/OR15-1, IGHV1OR151
  • Links
    NCBI Gene ID: 388077

  • Chr Location
    15q11.2; chr15:22160289-22160930 (-)  GRCh38
  • Human Ortholog
    IGHV1OR15-9, immunoglobulin heavy variable 1/OR15-9 (non-functional)
  • Synonyms
    IGHV1OR159, VSIG7
  • Links
    NCBI Gene ID: 390531

  • Chr Location
    15q11.1; chr15:19964656-19965101 (-)  GRCh38
  • Human Ortholog
    IGHV1OR21-1, immunoglobulin heavy variable 1/OR21-1 (non-functional)
  • Links
    NCBI Gene ID: 390530

  • Chr Location
    21p11.2; chr21:10649390-10649835 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
  • All Sequences
    22
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 780883 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
polypeptide A0A075B5U7 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory