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Ighv14-3 Gene Detail
Summary
  • Symbol
    Ighv14-3
  • Name
    immunoglobulin heavy variable V14-3
  • Synonyms
    Gm16840
  • Feature Type
    gene segment
  • IDs
    MGI:4439764
    NCBI Gene: 238418
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:114023465-114023893 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439764
gene segment Chr12:114023465-114023941 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000057
gene segment Chr12:116654385-116654862 (-)
A/J MGP_AJ_G0000057
gene segment Chr12:112196694-112197171 (-)
AKR/J MGP_AKRJ_G0000059
gene segment Chr12:115553605-115554082 (-)
BALB/cJ MGP_BALBcJ_G0000055
gene segment Chr12:112645153-112645630 (-)
C3H/HeJ MGP_C3HHeJ_G0000056
gene segment Chr12:115916562-115917039 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000077
gene segment Chr12:120291786-120292262 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0000055
gene segment Chr12:124832350-124832827 (-)
DBA/2J MGP_DBA2J_G0000058
gene segment Chr12:111769164-111769641 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0000064
gene segment Chr12:116605972-116606448 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000062
gene segment Chr12:128086523-128086999 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000072
gene segment Chr12:114894452-114894929 (-)
PWK/PhJ MGP_PWKPhJ_G0000048
gene segment Chr12:106310615-106412948 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38

  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1-F, IGHV1F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 238418 NCBI Gene Model | MGI Sequence Detail 429 C57BL/6J ±  kb
transcript S58456 GenBank | ENA | DDBJ | MGI Sequence Detail 321 Not Specified  
polypeptide A0A075B5R9 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 6
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory