About   Help   FAQ
Ighv1-52 Gene Detail
Summary
  • Symbol
    Ighv1-52
  • Name
    immunoglobulin heavy variable 1-52
  • Synonyms
    Gm16828
Location &
Maps
more
  • Sequence Map
    Chr12:115109107-115109400 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.51 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    173 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439752
gene segment Chr12:115109107-115109539 (-)
129S1/SvImJ no annotation
A/J ENSMUSG00195049145
gene segment Chr12:109663299-109663732 (-)
AKR/J ENSMUSG00220042482
gene segment Chr12:107308763-107309195 (-)
BALB/cJ no annotation
C3H/HeJ ENSMUSG00175045521
gene segment Chr12:111099715-111100147 (-)
C57BL/6NJ ENSMUSG00215049226
gene segment Chr12:107976446-107976878 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J ENSMUSG00210032030
gene segment Chr12:108375870-108376302 (-)
DBA/2J ENSMUSG00185014935
gene segment Chr12:111210588-111210611 (-)
FVB/NJ ENSMUSG00205044023
gene segment Chr12:108332588-108333020 (-)
JF1/MsJ ENSUMUG00000031282
gene segment Chr12:114846471-114846903 (-)
LP/J ENSMUSG00230049462
gene segment Chr12:117200394-117200826 (-)
NOD/ShiLtJ ENSMUSG00190034274
gene segment Chr12:106814799-106815231 (-)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010052005
gene segment Chr12:108575726-108576159 (-)
SPRET/EiJ ENSMSPG00010022088
gene segment Chr12:111148241-111148674 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Vertebrate Orthologs
    16
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-18, immunoglobulin heavy variable 1-18
  • Synonyms
    IGHV118
  • Links
    NCBI Gene ID: 28468
    UniProt: A0A0C4DH31

  • Chr Location
    14q32.33; chr14:106184899-106185394 (-)  GRCh38

  • Human Ortholog
    IGHV1-2, immunoglobulin heavy variable 1-2
  • Synonyms
    IGHV12, V35
  • Links
    NCBI Gene ID: 28474

  • Chr Location
    14q32.33; chr14:105986582-105987083 (-)  GRCh38

  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38

  • Human Ortholog
    IGHV1-3, immunoglobulin heavy variable 1-3
  • Synonyms
    IGHV13, VI-3B
  • Links
    NCBI Gene ID: 28473
    UniProt: A0A0C4DH29

  • Chr Location
    14q32.33; chr14:106005095-106005574 (-)  GRCh38

  • Human Ortholog
    IGHV1-38-4, immunoglobulin heavy variable 1-38-4 (non-functional)
  • Synonyms
    IGHV1-C, IGHV1C
  • Links
    NCBI Gene ID: 28460
    UniProt: P0DTW3

  • Chr Location
    14q32.33

  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Synonyms
    IGHV145, VH
  • Links
    NCBI Gene ID: 28466
    UniProt: A0A0A0MS14

  • Chr Location
    14q32.33; chr14:106506996-106507491 (-)  GRCh38

  • Human Ortholog
    IGHV1-46, immunoglobulin heavy variable 1-46
  • Synonyms
    IGHV146
  • Links
    NCBI Gene ID: 28465

  • Chr Location
    14q32.33; chr14:106511115-106511856 (-)  GRCh38

  • Human Ortholog
    IGHV1-58, immunoglobulin heavy variable 1-58
  • Synonyms
    IGHV158, VH
  • Links
    NCBI Gene ID: 28464
    UniProt: A0A0C4DH39

  • Chr Location
    14q32.33; chr14:106622357-106622855 (-)  GRCh38

  • Human Ortholog
    IGHV1-69, immunoglobulin heavy variable 1-69
  • Synonyms
    IGHV169, IGHV1-E, IGHV1E
  • Links
    NCBI Gene ID: 28461
    UniProt: P01742

  • Chr Location
    14q32.33; chr14:106714682-106715181 (-)  GRCh38

  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1-F, IGHV1F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38

  • Human Ortholog
    IGHV1-69D, immunoglobulin heavy variable 1-69D
  • Links
    NCBI Gene ID: 102723169
    UniProt: A0A0B4J2H0

  • Chr Location
    14q32.33; chr14:106762092-106762588 (-)  GRCh38

  • Human Ortholog
    IGHV1-8, immunoglobulin heavy variable 1-8
  • Synonyms
    IGHV18
  • Links
    NCBI Gene ID: 28472
    UniProt: P0DP01

  • Chr Location
    14q32.33

  • Human Ortholog
    IGHV1OR15-1, immunoglobulin heavy variable 1/OR15-1 (non-functional)
  • Synonyms
    IGHV1/OR15-1, IGHV1OR151
  • Links
    NCBI Gene ID: 388077

  • Chr Location
    15q11.2; chr15:22160289-22160930 (-)  GRCh38

  • Human Ortholog
    IGHV1OR15-9, immunoglobulin heavy variable 1/OR15-9 (non-functional)
  • Synonyms
    IGHV1OR159, VSIG7
  • Links
    NCBI Gene ID: 390531

  • Chr Location
    15q11.1; chr15:19964656-19965101 (-)  GRCh38

  • Human Ortholog
    IGHV1OR21-1, immunoglobulin heavy variable 1/OR21-1 (non-functional)
  • Links
    NCBI Gene ID: 390530

  • Chr Location
    21p11.2; chr21:10649390-10649835 (-)  GRCh38

Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 382696 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
polypeptide A0A0A6YXC3 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 5
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/01/2026
MGI 6.24
The Jackson Laboratory