Ighv1-9 MGI Mouse Gene Detail - MGI:4439621 - immunoglobulin heavy variable 1-9

Symbol

Ighv1-9
Name

immunoglobulin heavy variable 1-9
Synonyms

Gm16697

Feature Type

gene segment
IDs

MGI:4439621
NCBI Gene: 668478
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr12:114547189-114547482 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 62.40 cM
Mapping Data

1 experiment

SNPs within 2kb

270 from dbSNP Build 142
Strain Annotations

20

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439621	gene segment	Chr12:114547189-114547622 (-)
129S1/SvImJ	ENSMUSG00200030329	gene segment	Chr12:106253972-106254405 (-)
A/J	ENSMUSG00195048875	gene segment	Chr12:109028203-109028636 (-)
AKR/J	ENSMUSG00220042288	gene segment	Chr12:106733159-106733591 (-)
BALB/cJ	ENSMUSG00180052724	gene segment	Chr12:108486074-108486507 (-)
C3H/HeJ	ENSMUSG00175048162	gene segment	Chr12:110718073-110718505 (-)
C57BL/6NJ	ENSMUSG00215048500	gene segment	Chr12:107337032-107337465 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0000059	gene segment	Chr12:109092684-109093117 (-)
CAST/EiJ	ENSTCUG00005042791	gene segment	Chr12:107831996-107832429 (-)
CAST/EiJ	ENSTCUG00005042777	gene segment	Chr12:107475689-107476122 (-)
CBA/J	ENSMUSG00210040055	gene segment	Chr12:107794565-107794997 (-)
DBA/2J	ENSMUSG00185035750	gene segment	Chr12:109784926-109785359 (-)
FVB/NJ	ENSMUSG00205042058	gene segment	Chr12:106762333-106762766 (-)
JF1/MsJ	ENSUMUG00000029033	gene segment	Chr12:114333738-114334171 (-)
LP/J	ENSMUSG00230048604	gene segment	Chr12:116599715-116600148 (-)
NOD/ShiLtJ	ENSMUSG00190029078	gene segment	Chr12:106182855-106183288 (-)
NZO/HlLtJ	ENSMUSG00225043617	gene segment	Chr12:118535751-118536183 (-)
PWK/PhJ	ENSLUMG00010049082	gene segment	Chr12:108050951-108051384 (-)
SPRET/EiJ	ENSMSPG00010022813	gene segment	Chr12:110727406-110727839 (-)
WSB/EiJ	ENSIUOG00005040861	gene segment	Chr12:107261518-107261951 (-)

Human Ortholog

IGHV1-18, immunoglobulin heavy variable 1-18

Vertebrate Orthologs

16

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

IGHV1-18, immunoglobulin heavy variable 1-18
Synonyms

IGHV118
Links

HGNC:5549

NCBI Gene ID: 28468

UniProt: A0A0C4DH31
Chr Location

14q32.33; chr14:106184899-106185394 (-) GRCh38

Human Ortholog

IGHV1-2, immunoglobulin heavy variable 1-2
Synonyms

IGHV12, V35
Links

HGNC:5550

NCBI Gene ID: 28474
Chr Location

14q32.33; chr14:105986582-105987083 (-) GRCh38

Human Ortholog

IGHV1-24, immunoglobulin heavy variable 1-24
Synonyms

IGHV124, VH
Links

HGNC:5551

NCBI Gene ID: 28467

UniProt: A0A0C4DH33
Chr Location

14q32.33; chr14:106276546-106277043 (-) GRCh38

Human Ortholog

IGHV1-3, immunoglobulin heavy variable 1-3
Synonyms

IGHV13, VI-3B
Links

HGNC:5552

NCBI Gene ID: 28473

UniProt: A0A0C4DH29
Chr Location

14q32.33; chr14:106005095-106005574 (-) GRCh38

Human Ortholog

IGHV1-38-4, immunoglobulin heavy variable 1-38-4 (non-functional)
Synonyms

IGHV1-C, IGHV1C
Links

HGNC:5560

NCBI Gene ID: 28460

UniProt: P0DTW3
Chr Location

14q32.33

Human Ortholog

IGHV1-45, immunoglobulin heavy variable 1-45
Synonyms

IGHV145, VH
Links

HGNC:5553

NCBI Gene ID: 28466

UniProt: A0A0A0MS14
Chr Location

14q32.33; chr14:106506996-106507491 (-) GRCh38

Human Ortholog

IGHV1-46, immunoglobulin heavy variable 1-46
Synonyms

IGHV146
Links

HGNC:5554

NCBI Gene ID: 28465
Chr Location

14q32.33; chr14:106511115-106511856 (-) GRCh38

Human Ortholog

IGHV1-58, immunoglobulin heavy variable 1-58
Synonyms

IGHV158, VH
Links

HGNC:5555

NCBI Gene ID: 28464

UniProt: A0A0C4DH39
Chr Location

14q32.33; chr14:106622357-106622855 (-) GRCh38

Human Ortholog

IGHV1-69, immunoglobulin heavy variable 1-69
Synonyms

IGHV169, IGHV1-E, IGHV1E
Links

HGNC:5558

NCBI Gene ID: 28461

UniProt: P01742
Chr Location

14q32.33; chr14:106714682-106715181 (-) GRCh38

Human Ortholog

IGHV1-69-2, immunoglobulin heavy variable 1-69-2
Synonyms

IGHV1-F, IGHV1F
Links

HGNC:5562

NCBI Gene ID: 28458

UniProt: A0A0G2JMI3
Chr Location

14q32.33; chr14:106737110-106737547 (-) GRCh38

Human Ortholog

IGHV1-69D, immunoglobulin heavy variable 1-69D
Links

HGNC:49601

NCBI Gene ID: 102723169

UniProt: A0A0B4J2H0
Chr Location

14q32.33; chr14:106762092-106762588 (-) GRCh38

Human Ortholog

IGHV1-8, immunoglobulin heavy variable 1-8
Synonyms

IGHV18
Links

HGNC:5559

NCBI Gene ID: 28472

UniProt: P0DP01
Chr Location

14q32.33

Human Ortholog

IGHV1OR15-1, immunoglobulin heavy variable 1/OR15-1 (non-functional)
Synonyms

IGHV1/OR15-1, IGHV1OR151
Links

HGNC:5563

NCBI Gene ID: 388077
Chr Location

15q11.2; chr15:22160289-22160930 (-) GRCh38

Human Ortholog

IGHV1OR15-9, immunoglobulin heavy variable 1/OR15-9 (non-functional)
Synonyms

IGHV1OR159, VSIG7
Links

HGNC:5569

NCBI Gene ID: 390531
Chr Location

15q11.1; chr15:19964656-19965101 (-) GRCh38

Human Ortholog

IGHV1OR21-1, immunoglobulin heavy variable 1/OR21-1 (non-functional)
Links

HGNC:38040

NCBI Gene ID: 390530
Chr Location

21p11.2; chr21:10649390-10649835 (-) GRCh38

MGI Vertebrate Homology

Ighv1-9 stringent orthology
15 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: IGHV1-18, IGHV1-2, IGHV1-24, IGHV1-3, IGHV1-38-4, IGHV1-45, IGHV1-46, IGHV1-58, IGHV1-69, IGHV1-69-2, IGHV1-69D, IGHV1-8, IGHV1OR15-1, IGHV1OR15-9, IGHV1OR21-1
Gene Tree

Ighv1-9

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Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

11 strains or lines available

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

26
RefSeq

1
UniProt

1

Ensembl

ENSMUSG00000094694 (Evidence)
NCBI Gene

668478

Representative Sequences				Length	Strain/Species	Flank
	genomic	668478	NCBI Gene Model \| MGI Sequence Detail	294	C57BL/6J	± kb
	polypeptide	A0A0A6YW37	UniProt \| EBI \| MGI Sequence Detail	117	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR050199 Immunoglobulin Heavy Variable

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR013106 Immunoglobulin V-set domain

Summaries

All 7
Earliest

J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Latest

J:167375 Nimmerjahn F, et al., FcgammaRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19396-401

TSS for Ighv1-9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118090	Chr12:114547654-114547683 (-)	-187 bp
Tssr118089	Chr12:114547635-114547642 (-)	-157 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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