Igkv18-36 Gene Detail

Summary

• Symbol
  Igkv18-36
• Name
  immunoglobulin kappa chain variable 18-36
• Synonyms
  Gm16689

• Feature Type
  gene segment
• IDs
  MGI:4439613
  NCBI Gene: 620088
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr6:69969449-69969961 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 31.71 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  196 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439613	gene segment	Chr6:69969449-69969961 (-)
129S1/SvImJ	ENSMUSG00200013886	gene segment	Chr6:66875935-66876447 (-)
A/J	ENSMUSG00195046057	gene segment	Chr6:66634418-66634930 (-)
AKR/J	ENSMUSG00220045042	gene segment	Chr6:65704237-65704745 (-)
BALB/cJ	ENSMUSG00180043589	gene segment	Chr6:66990298-66990810 (-)
C3H/HeJ	ENSMUSG00175013151	gene segment	Chr6:110465052-110465564 (+)
C57BL/6NJ	ENSMUSG00215043596	gene segment	Chr6:66959302-66959814 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0000076	gene segment	Chr6:67118295-67118804 (-)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210042468	gene segment	Chr6:66782114-66782626 (-)
DBA/2J	ENSMUSG00185045076	gene segment	Chr6:67347327-67347839 (-)
FVB/NJ	ENSMUSG00205043634	gene segment	Chr6:66331346-66331859 (-)
JF1/MsJ	ENSUMUG00000046152	gene segment	Chr6:66426230-66426738 (-)
LP/J	ENSMUSG00230030260	gene segment	Chr6:68467611-68468123 (-)
NOD/ShiLtJ	ENSMUSG00190039007	gene segment	Chr6:66366958-66367466 (-)
NZO/HlLtJ	ENSMUSG00225021249	gene segment	Chr6:70441476-70441988 (-)
PWK/PhJ	ENSLUMG00010023770	gene segment	Chr6:65765583-65766089 (-)
SPRET/EiJ	ENSMSPG00010027789	gene segment	Chr6:67808050-67808559 (-)
WSB/EiJ	ENSIUOG00005026446	gene segment	Chr6:67628937-67629446 (-)

Homology

• Human Ortholog
  IGKV3-11, immunoglobulin kappa variable 3-11

• Vertebrate Orthologs
  10

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGKV3-11, immunoglobulin kappa variable 3-11
  
• Synonyms
  IGKV311, L6
• Links
  HGNC:5815

  NCBI Gene ID: 28914

  
  
• Chr Location
  2p11.2; chr2:89027171-89027731 (-)  GRCh38

---

• Human Ortholog
  IGKV3-15, immunoglobulin kappa variable 3-15
  
• Synonyms
  IGKV315, L2
• Links
  HGNC:5816

  NCBI Gene ID: 28913

  UniProt: P01624

  
  
• Chr Location
  2p11.2; chr2:89085177-89085787 (-)  GRCh38

---

• Human Ortholog
  IGKV3-20, immunoglobulin kappa variable 3-20
  
• Synonyms
  13K18, A27, IGKV320
• Links
  HGNC:5817

  NCBI Gene ID: 28912

  UniProt: P01619

  
  
• Chr Location
  2p11.2; chr2:89142574-89143160 (-)  GRCh38

---

• Human Ortholog
  IGKV3-7, immunoglobulin kappa variable 3-7 (non-functional)
  
• Synonyms
  IGKV37, L10, L10a, Vh
• Links
  HGNC:5821

  NCBI Gene ID: 28915

  UniProt: A0A075B6H7

  
  
• Chr Location
  2p11.2; chr2:88978468-88979081 (-)  GRCh38

---

• Human Ortholog
  IGKV3D-11, immunoglobulin kappa variable 3D-11
  
• Synonyms
  IGKV3D11, L20
• Links
  HGNC:5823

  NCBI Gene ID: 28876

  UniProt: A0A0A0MRZ8

  
  
• Chr Location
  2p11.2; chr2:90172802-90173414 (+)  GRCh38

---

• Human Ortholog
  IGKV3D-15, immunoglobulin kappa variable 3D-15
  
• Synonyms
  IGKV3D15, L16, L16a, L16b, L16c
• Links
  HGNC:5824

  NCBI Gene ID: 28875

  UniProt: A0A087WSY6

  
  
• Chr Location
  2p11.2; chr2:90114838-90115402 (+)  GRCh38

---

• Human Ortholog
  IGKV3D-20, immunoglobulin kappa variable 3D-20
  
• Synonyms
  A11, A11a, IGKV3D20
• Links
  HGNC:5825

  NCBI Gene ID: 28874

  UniProt: A0A0C4DH25

  
  
• Chr Location
  2p11.2; chr2:90038848-90039479 (+)  GRCh38

---

• Human Ortholog
  IGKV3D-7, immunoglobulin kappa variable 3D-7
  
• Synonyms
  IGKV3D7, L25
• Links
  HGNC:5829

  NCBI Gene ID: 28877

  UniProt: A0A0C4DH55

  
  
• Chr Location
  2p11.2; chr2:90234812-90235370 (+)  GRCh38

---

• Human Ortholog
  IGKV3OR2-268, immunoglobulin kappa variable 3/OR2-268 (non-functional)
  
• Synonyms
  IGKV268, IGKV3OR2268, IGKV3OR2-268A, IGKV3OR2268A
• Links
  HGNC:5830

  NCBI Gene ID: 3523

  
  
• Chr Location
  2p12; chr2:87338511-87339035 (+)  GRCh38

---

• MGI Vertebrate Homology
  Igkv18-36 stringent orthology
  9 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: IGKV3-11, IGKV3-15, IGKV3-20, IGKV3-7, IGKV3D-11, IGKV3D-15, IGKV3D-20, IGKV3D-7, IGKV3OR2-268
• Gene Tree
  Igkv18-36
  

Gene Ontology
(GO)
Classifications

• All GO Annotations
  6
• GO References
  2

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000076572 (Evidence)
• NCBI Gene
  620088

Representative Sequences			Length	Strain/Species
genomic	620088	NCBI Gene Model | MGI Sequence Detail	513	C57BL/6J
polypeptide	A0A0G2JEE1	UniProt | EBI | MGI Sequence Detail	113	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR003599 Immunoglobulin domain subtype
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR003598 Immunoglobulin subtype 2
  IPR050150 Immunoglobulin Variable Light Chain
  IPR013106 Immunoglobulin V-set domain

References

• Summaries
  All 8

  Gene Ontology 2
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Igkv18-36:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr61306	Chr6:69969977-69969993 (-)	-24 bp