Gm16685 Gene Detail

Summary

• Symbol
  Gm16685
• Name
  predicted gene, 16685
• Synonyms
  mNAIL, NAIL

• Feature Type
  lncRNA gene
• IDs
  MGI:4439609
  NCBI Gene: 102634900
• Alliance
  genome feature page
• Transcription Start Sites
  21 TSS

Location &
Maps

• Sequence Map
  Chr3:7677765-7755061 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 2.02 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  2673 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439609	lncRNA gene	Chr3:7641280-7814826 (+)
129S1/SvImJ	ENSMUSG00200000908	lncRNA gene	Chr3:4327424-4405096 (+)
A/J	ENSMUSG00195001235	lncRNA gene	Chr3:4667158-4744801 (+)
AKR/J	ENSMUSG00220017220	lncRNA gene	Chr3:4659422-4737062 (+)
BALB/cJ	ENSMUSG00180007484	lncRNA gene	Chr3:4666664-4744295 (+)
C3H/HeJ	ENSMUSG00175005199	lncRNA gene	Chr3:4677996-4755631 (+)
C57BL/6NJ	ENSMUSG00215005546	lncRNA gene	Chr3:4701456-4779132 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003333	antisense lncRNA gene	Chr3:3772617-3850814 (+)
CAST/EiJ	ENSTCUG00005000251	lncRNA gene	Chr3:4721103-4798190 (+)
CBA/J	ENSMUSG00210000671	lncRNA gene	Chr3:4663178-4740813 (+)
DBA/2J	ENSMUSG00185000552	lncRNA gene	Chr3:4647321-4724349 (+)
FVB/NJ	ENSMUSG00205006210	lncRNA gene	Chr3:4475608-4552635 (+)
JF1/MsJ	ENSUMUG00000010373	lncRNA gene	Chr3:4548769-4625250 (+)
LP/J	ENSMUSG00230000165	lncRNA gene	Chr3:6601046-6678701 (+)
NOD/ShiLtJ	ENSMUSG00190023647	lncRNA gene	Chr3:4738472-4815502 (+)
NZO/HlLtJ	ENSMUSG00225001687	lncRNA gene	Chr3:9140103-9217707 (+)
PWK/PhJ	ENSLUMG00010008441	lncRNA gene	Chr3:4601997-4678479 (+)
SPRET/EiJ	ENSMSPG00010000138	lncRNA gene	Chr3:4477472-4561661 (+)
WSB/EiJ	ENSIUOG00005000845	lncRNA gene	Chr3:4684545-4762189 (+)

Homology

• Gene Tree
  Gm16685
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  3
• Gene trapped
  3
• Find Mice (IMSR)
  2 strains or lines available

Homozygous knockout reduces susceptibility to induced colitis.

Expression

• Assay Results
  597
• cDNA Data
  3

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  43
• RefSeq
  1

• Ensembl
  ENSMUSG00000097804 (Evidence)
• NCBI Gene
  102634900

Representative Sequences			Length	Strain/Species
genomic	102634900	NCBI Gene Model | MGI Sequence Detail	77297	C57BL/6J
transcript	NR_168341	RefSeq | MGI Sequence Detail	1592	ZRU/MplStud

Molecular
Reagents

• All nucleic 3

  cDNA 3

References

• Summaries
  All 8

  Phenotypes 3
• Earliest
  J:303079 Akincilar SC, et al., NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFkappaB in colitis. Gut. 2020 Nov 25;

TSS for Gm16685:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr28303	Chr3:7677762-7677765 (+)	-1 bp
Tssr28304	Chr3:7678931-7678949 (+)	1,175 bp
Tssr28305	Chr3:7681053-7681063 (+)	3,293 bp
Tssr28306	Chr3:7682403-7682435 (+)	4,654 bp
Tssr28307	Chr3:7683791-7683804 (+)	6,033 bp
Tssr28308	Chr3:7683827-7683842 (+)	6,070 bp
Tssr28309	Chr3:7683939-7683952 (+)	6,181 bp
Tssr28310	Chr3:7685203-7685206 (+)	7,440 bp
Tssr28311	Chr3:7689681-7689702 (+)	11,927 bp
Tssr28312	Chr3:7691964-7692002 (+)	14,218 bp
Tssr28313	Chr3:7694263-7694301 (+)	16,517 bp
Tssr28314	Chr3:7700860-7700864 (+)	23,097 bp
Tssr28315	Chr3:7709628-7709667 (+)	31,883 bp
Tssr28316	Chr3:7711856-7711875 (+)	34,101 bp
Tssr28317	Chr3:7711971-7711981 (+)	34,211 bp
Tssr28318	Chr3:7712001-7712013 (+)	34,242 bp
Tssr28319	Chr3:7712133-7712151 (+)	34,377 bp
Tssr28320	Chr3:7712161-7712171 (+)	34,401 bp
Tssr28321	Chr3:7712215-7712230 (+)	34,458 bp
Tssr28322	Chr3:7725337-7725366 (+)	47,587 bp
Tssr28323	Chr3:7751976-7752011 (+)	74,229 bp