Dynlt1f Gene Detail

Summary

• Symbol
  Dynlt1f
• Name
  dynein light chain Tctex-type 1F
• Synonyms
  Dynlt1e

• Feature Type
  protein coding gene
• IDs
  MGI:3780996
  NCBI Gene: 100040531
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr17:6914001-6923299 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 4.11 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  123 from dbSNP Build 142
• Strain Annotations
  3

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3780996	protein coding gene	Chr17:6914001-6923338 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	ENSMUSG00185023024	protein coding gene	Chr17:3893138-3902692 (-)
FVB/NJ	no annotation
JF1/MsJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	ENSMUSG00225028790	protein coding gene	Chr17:7245126-7261560 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  DYNLT1, dynein light chain Tctex-type 1

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  DYNLT1, dynein light chain Tctex-type 1
  
• Synonyms
  CW-1, TCTEL1, tctex-1, TCTEX1
• Links
  HGNC:11697

  NCBI Gene ID: 6993

  UniProt: P63172

  
  
• Chr Location
  6q25.3; chr6:158636474-158644755 (-)  GRCh38

---

• MGI Vertebrate Homology
  Dynlt1f stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: DYNLT1
• Gene Tree
  Dynlt1f
  

Human Diseases

• References
  6 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  374 phenotype references
  

• All Mutations and Alleles
  3
• Gene trapped
  2
• Radiation induced
  1
• Genomic Mutations
  1 involving Dynlt1f
• Find Mice (IMSR)
  9 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  18
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS49939.1, CCDS57043.1

• Ensembl
  ENSMUSG00000095677 (Evidence)
• NCBI Gene
  100040531

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000095677	Ensembl Gene Model | MGI Sequence Detail	9299	C57BL/6J
transcript	ENSMUST00000179554	Ensembl | MGI Sequence Detail	771	Not Applicable
polypeptide	ENSMUSP00000135978	Ensembl | MGI Sequence Detail	113	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 1

  cDNA 1

Other
Accession IDs

MGI:3781053

References

• Summaries
  All 386

  Diseases 6

  Phenotypes 374
• Earliest
  J:11036 Howard CA, et al., Genetic and molecular analysis of the proximal region of the mouse t-complex using new molecular probes and partial t-haplotypes. Genetics. 1990 Dec;126(4):1103-14
• Latest
  J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815