Krtap10-27 Gene Detail

Summary

• Symbol
  Krtap10-27
• Name
  keratin associated protein 10-27
• Synonyms
  Gm9507

• Feature Type
  protein coding gene
• IDs
  MGI:3779917
  NCBI Gene: 670880
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr10:77646801-77647677 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 39.72 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  113 from dbSNP Build 142
• Strain Annotations
  14

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3779917	protein coding gene	Chr10:77646581-77647723 (-)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0017385	protein coding gene	Chr10:75489991-75491803 (-)
AKR/J	MGP_AKRJ_G0017348	protein coding gene	Chr10:77517156-77519773 (-)
BALB/cJ	MGP_BALBcJ_G0017347	protein coding gene	Chr10:75676290-75676964 (-)
C3H/HeJ	MGP_C3HHeJ_G0017170	protein coding gene	Chr10:77588042-77588920 (-)
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0015494	protein coding gene	Chr10:71858440-71859287 (-)
CAST/EiJ	MGP_CASTEiJ_G0016740	protein coding gene	Chr10:77921658-77922254 (-)
CBA/J	MGP_CBAJ_G0017142	protein coding gene	Chr10:84031793-84032554 (-)
DBA/2J	MGP_DBA2J_G0017250	protein coding gene	Chr10:74738817-74740574 (-)
FVB/NJ	MGP_FVBNJ_G0017242	protein coding gene	Chr10:73908899-73909842 (-)
LP/J	MGP_LPJ_G0017322	protein coding gene	Chr10:78638697-78639152 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017269	protein coding gene	Chr10:86059463-86060902 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017845	protein coding gene	Chr10:77557033-77557866 (-)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0016307	protein coding gene	Chr10:76761671-76763494 (-)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  KRTAP10-10, keratin associated protein 10-10

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP10-10, keratin associated protein 10-10
  
• Synonyms
  KAP10.10, KAP18.10, KRTAP18-10, KRTAP18.10
• Links
  HGNC:22972

  NCBI Gene ID: 353333

  UniProt: P60014

  
  
• Chr Location
  21q22.3; chr21:44637356-44638455 (+)  GRCh38

---

• Human Ortholog
  KRTAP10-3, keratin associated protein 10-3
  
• Synonyms
  KAP10.3, KAP18-3, KAP18.3, KRTAP10.3, KRTAP18-3, KRTAP18.3
• Links
  HGNC:22968

  NCBI Gene ID: 386682

  UniProt: P60369

  
  
• Chr Location
  21q22.3; chr21:44557790-44558795 (-)  GRCh38

---

• Human Ortholog
  KRTAP10-7, keratin associated protein 10-7
  
• Synonyms
  KAP10.7, KAP18.7, KRTAP18-7
• Links
  HGNC:22970

  NCBI Gene ID: 386675

  UniProt: P60409

  
  
• Chr Location
  21q22.3; chr21:44600597-44602174 (+)  GRCh38

---

• MGI Vertebrate Homology
  Krtap10-27 stringent orthology
  3 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: KRTAP10-10, KRTAP10-3, KRTAP10-7
• Gene Tree
  Krtap10-27
  

Human Diseases

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  30 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Targeted
  3
• Genomic Mutations
  4 involving Krtap10-27
• Find Mice (IMSR)
  5 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS88039.1

• Ensembl
  ENSMUSG00000094913 (Evidence)
• NCBI Gene
  670880

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000094913	Ensembl Gene Model | MGI Sequence Detail	877	C57BL/6J
transcript	ENSMUST00000095491	Ensembl | MGI Sequence Detail	877	Not Applicable
polypeptide	ENSMUSP00000093145	Ensembl | MGI Sequence Detail	223	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR002494 Keratin-associated protein
• GlyGen
  D3Z5T3 1 site

Other
Accession IDs

MGI:7580648

References

• Summaries
  All 38

  Diseases 2

  Gene Ontology 1

  Phenotypes 30
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:361105 Tateossian H, et al., DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome. Elife. 2025;

TSS for Krtap10-27:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr98249	Chr10:77647718-77647724 (-)	-44 bp