Tmem181b-ps Pseudogene Detail

Summary

• Symbol
  Tmem181b-ps
• Name
  transmembrane protein 181B, pseudogene

• Feature Type
  pseudogene
• IDs
  MGI:3779544
  NCBI Gene: 547127
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr17:6706401-6718393 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 3.98 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  87 from dbSNP Build 142
• Strain Annotations
  26

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3779544	pseudogene	Chr17:6706401-6757783 (-)
129S1/SvImJ	ENSMUSG00200035321	pseudogene	Chr17:3216490-3244991 (+)
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	ENSMUSG00215017692	protein coding gene	Chr17:3386554-3387660 (-)
C57BL/6NJ	ENSMUSG00215032948	pseudogene	Chr17:3302007-3323067 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0036953	pseudogene	Chr17:3150149-3177528 (+)
CAST/EiJ	ENSTCUG00005022641	pseudogene	Chr17:3254561-3284297 (+)
CBA/J	no annotation
DBA/2J	ENSMUSG00185023003	protein coding gene	Chr17:3861397-3870250 (-)
DBA/2J	ENSMUSG00185023697	pseudogene	Chr17:3650238-3678743 (+)
FVB/NJ	ENSMUSG00205007869	protein coding gene	Chr17:3432906-3434012 (-)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230033224	protein coding gene	Chr17:4579006-4587393 (-)
LP/J	ENSMUSG00230035567	pseudogene	Chr17:4431016-4442013 (+)
LP/J	ENSMUSG00230033527	protein coding gene	Chr17:5271325-5276501 (-)
LP/J	ENSMUSG00230035770	pseudogene	Chr17:5209907-5221330 (-)
LP/J	ENSMUSG00230035110	pseudogene	Chr17:4573991-4602496 (-)
LP/J	ENSMUSG00230035929	pseudogene	Chr17:4739574-4750795 (-)
NOD/ShiLtJ	ENSMUSG00190030651	protein coding gene	Chr17:4812913-4834827 (+)
NOD/ShiLtJ	ENSMUSG00190040569	pseudogene	Chr17:3359216-3387701 (-)
NOD/ShiLtJ	ENSMUSG00190035294	protein coding gene	Chr17:3541220-3542216 (-)
NZO/HlLtJ	ENSMUSG00225029263	pseudogene	Chr17:6877073-6888496 (-)
NZO/HlLtJ	ENSMUSG00225028767	protein coding gene	Chr17:6887274-6888271 (-)
NZO/HlLtJ	ENSMUSG00225029131	pseudogene	Chr17:7043806-7072311 (-)
NZO/HlLtJ	ENSMUSG00225028783	protein coding gene	Chr17:7218502-7228196 (-)
NZO/HlLtJ	ENSMUSG00225029257	pseudogene	Chr17:6734982-6745979 (+)
PWK/PhJ	ENSLUMG00010019881	pseudogene	Chr17:3390218-3410037 (-)
SPRET/EiJ	ENSMSPG00010037950	pseudogene	Chr17:3238140-3254557 (+)
WSB/EiJ	ENSIUOG00005014732	pseudogene	Chr17:3262430-3284313 (-)

Homology

• Gene Tree
  Tmem181b-ps
  

Human Diseases

• References
  6 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  372 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Genomic Mutations
  1 involving Tmem181b-ps
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  597
• cDNA Data
  3

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  43
• RefSeq
  1
• UniProt
  3

• Ensembl
  ENSMUSG00000096780 (Evidence)
• NCBI Gene
  547127

Representative Sequences			Length	Strain/Species
genomic	547127	NCBI Gene Model | MGI Sequence Detail	11993	C57BL/6J
transcript	NR_033520	RefSeq | MGI Sequence Detail	4710	C57BL/6
polypeptide	B2RVR2	UniProt | EBI | MGI Sequence Detail	474	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR054077 TMEM181, GOLD domain
  IPR040416 Transmembrane protein 181
  IPR047843 Wntless-like, transmembrane domain

Molecular
Reagents

• All nucleic 6

  cDNA 6

  
  

  Microarray probesets 1

References

• Summaries
  All 381

  Diseases 6

  Phenotypes 372
• Earliest
  J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
• Latest
  J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815