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Tmem35b Gene Detail
Summary
  • Symbol
    Tmem35b
  • Name
    transmembrane protein 35B
  • Synonyms
    Zmym6nb
Location &
Maps
more
  • Sequence Map
    Chr4:127019836-127023453 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 61.29 cM
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3758095
 protein coding gene Chr4:127017484-127023453 (+)
129S1/SvImJ ENSMUSG00200011555
 protein coding gene Chr4:120456691-120462103 (+)
A/J ENSMUSG00195027278
 protein coding gene Chr4:121793151-121798563 (+)
AKR/J ENSMUSG00220020355
 protein coding gene Chr4:120773304-120778750 (+)
BALB/cJ ENSMUSG00180043719
 protein coding gene Chr4:119426916-119432328 (+)
C3H/HeJ ENSMUSG00175025079
 protein coding gene Chr4:120439616-120445028 (+)
C57BL/6NJ ENSMUSG00215049726
 protein coding gene Chr4:121936884-121942330 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026490
 protein coding gene Chr4:116899536-116905552 (+)
CAST/EiJ ENSTCUG00005043511
 protein coding gene Chr4:121322444-121327892 (+)
CBA/J ENSMUSG00210051293
 protein coding gene Chr4:120068493-120073905 (+)
DBA/2J ENSMUSG00185043187
 protein coding gene Chr4:121601133-121606545 (+)
FVB/NJ ENSMUSG00205016518
 protein coding gene Chr4:119813096-119818508 (+)
JF1/MsJ ENSUMUG00000012386
 protein coding gene Chr4:122236242-122241668 (+)
LP/J ENSMUSG00230029821
 protein coding gene Chr4:125394301-125399713 (+)
NOD/ShiLtJ ENSMUSG00190033033
 protein coding gene Chr4:119813537-119818949 (+)
NZO/HlLtJ ENSMUSG00225015308
 protein coding gene Chr4:131301005-131306417 (+)
PWK/PhJ ENSLUMG00010040558
 protein coding gene Chr4:119270935-119276355 (+)
SPRET/EiJ ENSMSPG00010036796
 protein coding gene Chr4:121341421-121346864 (+)
WSB/EiJ ENSIUOG00005044254
 protein coding gene Chr4:119671491-119676937 (+)



Homology
more
  • Human Ortholog
    TMEM35B, transmembrane protein 35B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM35B, transmembrane protein 35B
  • Synonyms
    ZMYM6NB
  • Links
    NCBI Gene ID: 100506144
    UniProt: Q8NCS4

  • Chr Location
    chr1:34981380-34985347 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Tmem35b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100039968 NCBI Gene Model | MGI Sequence Detail 3618 C57BL/6J ±  kb
transcript NM_001099319 RefSeq | MGI Sequence Detail 1139 C57BL/6  
polypeptide Q3U0Y2 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory