Ccl27al Gene Detail

Summary

• Symbol
  Ccl27al
• Name
  C-C motif chemokine ligand 27A like
• Synonyms
  Gm13306

• Feature Type
  protein coding gene
• IDs
  MGI:3713752
  NCBI Gene: 100039863
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr4:42153436-42158839 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 22.29 cM

Strain
Comparison

• Strain Annotations
  7

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3713752	protein coding gene	Chr4:42153404-42158846 (+)
129S1/SvImJ	ENSMUSG00200004142	protein coding gene	Chr4:38677578-38682998 (+)
A/J	no annotation
AKR/J	ENSMUSG00220031876	protein coding gene	Chr4:38926627-38931633 (-)
AKR/J	ENSMUSG00220031484	protein coding gene	Chr4:38817362-38819450 (-)
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
JF1/MsJ	no annotation
LP/J	ENSMUSG00230040250	protein coding gene	Chr4:42498254-42503797 (+)
NOD/ShiLtJ	ENSMUSG00190005114	protein coding gene	Chr4:38678609-38682742 (-)
NOD/ShiLtJ	ENSMUSG00190005141	protein coding gene	Chr4:38884348-38889355 (-)
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  CCL27, C-C motif chemokine ligand 27

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CCL27, C-C motif chemokine ligand 27
  
• Synonyms
  ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
• Links
  HGNC:10626

  NCBI Gene ID: 10850

  UniProt: Q9Y4X3

  
  
• Chr Location
  9p13.3; chr9:34661880-34664048 (-)  GRCh38

---

• MGI Vertebrate Homology
  Ccl27al stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: CCL27
• Gene Tree
  Ccl27al
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotypes from multigenic genotypes
  6 phenotype references
  

• All Mutations and Alleles
  5
• Chemically and radiation induced
  1
• Endonuclease-mediated
  1
• Targeted
  3
• Genomic Mutations
  1 involving Ccl27al
• Find Mice (IMSR)
  3 strains or lines available

Expression

• Assay Results
  709
• Tissues
  16
• cDNA Data
  3
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  49
• RefSeq
  26
• CCDS
  CCDS51149.1, CCDS57270.1

• Ensembl
  ENSMUSG00000073877 (Evidence)
• NCBI Gene
  100039863

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000073877	Ensembl Gene Model | MGI Sequence Detail	5404	C57BL/6J
transcript	ENSMUST00000108018	Ensembl | MGI Sequence Detail	542	Not Applicable
polypeptide	ENSMUSP00000103653	Ensembl | MGI Sequence Detail	135	Not Applicable

Molecular
Reagents

• All nucleic 4

  cDNA 4

Other
Accession IDs

MGI:7526409

References

• Summaries
  All 23

  Developmental Gene Expression 1

  Phenotypes 6
• Earliest
  J:55764 Hromas R, et al., Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension. Biochem Biophys Res Commun. 1999 May 19;258(3):737-40
• Latest
  J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426