Defa-ps10 Pseudogene Detail

Summary

• Symbol
  Defa-ps10
• Name
  defensin, alpha, pseudogene 10
• Synonyms
  OTTMUSG00000019929

• Feature Type
  pseudogene
• IDs
  MGI:3705783
  NCBI Gene: 100040729
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr8:22212086-22212256 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM

Strain
Comparison

• SNPs within 2kb
  83 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3705783	pseudogene	Chr8:22212073-22212257 (+)
129S1/SvImJ	ENSMUSG00200033931	pseudogene	Chr8:17260337-17260507 (+)
A/J	ENSMUSG00195044315	pseudogene	Chr8:17811769-17811939 (+)
AKR/J	ENSMUSG00220034965	pseudogene	Chr8:17428210-17428380 (+)
BALB/cJ	ENSMUSG00180027007	pseudogene	Chr8:17336427-17336597 (+)
C3H/HeJ	ENSMUSG00175039841	pseudogene	Chr8:17402801-17402971 (+)
C57BL/6NJ	ENSMUSG00215030604	pseudogene	Chr8:17268186-17268356 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005019816	pseudogene	Chr8:17645779-17645949 (+)
CBA/J	ENSMUSG00210043954	pseudogene	Chr8:17336079-17336249 (+)
DBA/2J	ENSMUSG00185041372	pseudogene	Chr8:23139021-23139191 (+)
FVB/NJ	ENSMUSG00205032595	pseudogene	Chr8:16828921-16829091 (+)
JF1/MsJ	ENSUMUG00000030186	pseudogene	Chr8:25020361-25020531 (+)
LP/J	ENSMUSG00230011744	pseudogene	Chr8:26900224-26900394 (+)
NOD/ShiLtJ	ENSMUSG00190037853	pseudogene	Chr8:17369578-17369748 (+)
NZO/HlLtJ	ENSMUSG00225021807	pseudogene	Chr8:30508378-30508548 (+)
PWK/PhJ	ENSLUMG00010031971	pseudogene	Chr8:17389233-17389403 (+)
SPRET/EiJ	ENSMSPG00010015211	pseudogene	Chr8:17415237-17415407 (+)
WSB/EiJ	ENSIUOG00005021608	pseudogene	Chr8:18059448-18059618 (+)

Homology

• Gene Tree
  Defa-ps10
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps10
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• RefSeq
  1

• Ensembl
  ENSMUSG00000096340 (Evidence)
• NCBI Gene
  100040729

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000096340	Ensembl Gene Model | MGI Sequence Detail	171	C57BL/6J
transcript	ENSMUST00000121649	Ensembl | MGI Sequence Detail	171	Not Applicable

References

• Summaries
  All 6

  Phenotypes 1
• Earliest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662

TSS for Defa-ps10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr76556	Chr8:22212040-22212041 (+)	-45 bp