Defa-ps7 Pseudogene Detail

Summary

• Symbol
  Defa-ps7
• Name
  defensin, alpha, pseudogene 7
• Synonyms
  OTTMUSG00000019817

• Feature Type
  pseudogene
• IDs
  MGI:3705773
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr8:21722082-21722249 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM

Strain
Comparison

• SNPs within 2kb
  15 from dbSNP Build 142
• Strain Annotations
  22

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3705773	pseudogene	Chr8:21722082-21722249 (-)
129S1/SvImJ	ENSMUSG00200034029	pseudogene	Chr8:17138587-17138754 (-)
129S1/SvImJ	ENSMUSG00200034205	pseudogene	Chr8:17049108-17049275 (-)
A/J	ENSMUSG00195043729	pseudogene	Chr8:17690019-17690186 (-)
A/J	ENSMUSG00195044866	pseudogene	Chr8:17600525-17600692 (-)
AKR/J	ENSMUSG00220033508	pseudogene	Chr8:17410735-17410902 (-)
BALB/cJ	ENSMUSG00180028073	pseudogene	Chr8:17214678-17214845 (-)
BALB/cJ	ENSMUSG00180028173	pseudogene	Chr8:17125193-17125360 (-)
C3H/HeJ	ENSMUSG00175040669	pseudogene	Chr8:17337580-17337747 (-)
C57BL/6NJ	ENSMUSG00215028799	pseudogene	Chr8:16926138-16926305 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005020106	pseudogene	Chr8:17414510-17414677 (-)
CAST/EiJ	ENSTCUG00005019345	pseudogene	Chr8:17547604-17547771 (-)
CBA/J	ENSMUSG00210044742	pseudogene	Chr8:17214331-17214498 (-)
CBA/J	ENSMUSG00210045085	pseudogene	Chr8:17124847-17125014 (-)
DBA/2J	ENSMUSG00185042303	pseudogene	Chr8:22927775-22927942 (-)
DBA/2J	ENSMUSG00185040011	pseudogene	Chr8:23017273-23017440 (-)
FVB/NJ	no annotation
JF1/MsJ	ENSUMUG00000032727	pseudogene	Chr8:24931290-24931457 (-)
JF1/MsJ	ENSUMUG00000030555	pseudogene	Chr8:24847722-24847889 (-)
LP/J	ENSMUSG00230012120	pseudogene	Chr8:26766725-26766892 (-)
NOD/ShiLtJ	no annotation
NZO/HlLtJ	ENSMUSG00225042244	pseudogene	Chr8:30018364-30018531 (-)
PWK/PhJ	ENSLUMG00010031665	pseudogene	Chr8:17158838-17159005 (-)
PWK/PhJ	ENSLUMG00010031712	pseudogene	Chr8:17288313-17288480 (-)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Defa-ps7
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps7
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24

• Ensembl
  ENSMUSG00000080722 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000080722	Ensembl Gene Model | MGI Sequence Detail	168	C57BL/6J
transcript	ENSMUST00000117139	Ensembl | MGI Sequence Detail	168	Not Applicable

References

• Summaries
  All 5

  Phenotypes 1
• Earliest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662

TSS for Defa-ps7:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr80564	Chr8:21722286-21722294 (-)	-41 bp