Trav7-6 Gene Detail

Summary

• Symbol
  Trav7-6
• Name
  T cell receptor alpha variable 7-6

• Feature Type
  gene segment
• IDs
  MGI:3702133
  NCBI Gene: 213480
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:53954217-53954748 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.48 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  63 from dbSNP Build 142
• Strain Annotations
  9

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3702133	gene segment	Chr14:53954173-53954748 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0002550	gene segment	Chr14:47259891-47260467 (+)
A/J	no annotation
AKR/J	MGP_AKRJ_G0002503	gene segment	Chr14:47846608-47847184 (+)
BALB/cJ	MGP_BALBcJ_G0002503	gene segment	Chr14:45952405-45952679 (+)
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0002230	gene segment	Chr14:45092604-45092878 (-)
CAST/EiJ	MGP_CASTEiJ_G0002474	gene segment	Chr14:44346127-44346401 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0002656	gene segment	Chr14:47147411-47147987 (+)
PWK/PhJ	MGP_PWKPhJ_G0002424	gene segment	Chr14:42614027-42614603 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0002382	gene segment	Chr14:43363908-43364182 (+)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  TRAV12-1, T cell receptor alpha variable 12-1

• Vertebrate Orthologs
  9

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV12-1, T cell receptor alpha variable 12-1
  
• Synonyms
  TCRAV12S1, TCRAV2S3, TRAV121
• Links
  HGNC:12105

  NCBI Gene ID: 28674

  UniProt: A0A0B4J245

  
  
• Chr Location
  14q11.2; chr14:21841240-21841774 (+)  GRCh38

---

• Human Ortholog
  TRAV12-2, T cell receptor alpha variable 12-2
  
• Synonyms
  TCRAV12S2, TCRAV2S1, TRAV122
• Links
  HGNC:12106

  NCBI Gene ID: 28673

  UniProt: A0A075B6T6

  
  
• Chr Location
  14q11.2; chr14:21887857-21888502 (+)  GRCh38

---

• Human Ortholog
  TRAV12-3, T cell receptor alpha variable 12-3
  
• Synonyms
  TCRAV12S3, TCRAV2S2, TRAV123
• Links
  HGNC:12107

  NCBI Gene ID: 28672

  UniProt: A0A0B4J271

  
  
• Chr Location
  14q11.2; chr14:21965451-21966061 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav7-6 stringent orthology
  3 human;1 mouse;6 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV12-1, TRAV12-2, TRAV12-3
• Gene Tree
  Trav7-6
  

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  19
• RefSeq
  2
• UniProt
  2

• Ensembl
  ENSMUSG00000096138 (Evidence)
• NCBI Gene
  213480

Representative Sequences			Length	Strain/Species
genomic	213480	NCBI Gene Model | MGI Sequence Detail	532	C57BL/6J
polypeptide	A0A075B640	UniProt | EBI | MGI Sequence Detail	112	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain

References

• Summaries
  All 11

  Gene Ontology 1
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Trav7-6:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125494	Chr14:53954137-53954163 (+)	-67 bp