Hnf1aos2 Gene Detail

Summary

• Symbol
  Hnf1aos2
• Name
  HNF1 homeobox A, opposite strand 2
• Synonyms
  Gm13825, Haster

• Feature Type
  antisense lncRNA gene
  BioType Conflict
  
• IDs
  MGI:3652220
• Alliance
  genome feature page
• Transcription Start Sites
  3 TSS
• Regulated by
  Rr124128 (1 regulatory region)

Location &
Maps

• Sequence Map
  Chr5:115106882-115109459 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 55.99 cM

Strain
Comparison

• SNPs within 2kb
  155 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3652220	antisense lncRNA gene	Chr5:115106882-115109459 (+)
129S1/SvImJ	ENSMUSG00200024638	lncRNA gene	Chr5:108849565-108852142 (+)
A/J	ENSMUSG00195040879	lncRNA gene	Chr5:108361397-108363976 (+)
AKR/J	ENSMUSG00220052052	lncRNA gene	Chr5:107878919-107881496 (+)
BALB/cJ	ENSMUSG00180046966	lncRNA gene	Chr5:108500255-108502832 (+)
C3H/HeJ	ENSMUSG00175047408	lncRNA gene	Chr5:110487349-110489930 (+)
C57BL/6NJ	ENSMUSG00215035335	lncRNA gene	Chr5:108507742-108510320 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003741	antisense lncRNA gene	Chr5:107914636-107917225 (+)
CAST/EiJ	ENSTCUG00005034027	lncRNA gene	Chr5:107681048-107683623 (+)
CBA/J	ENSMUSG00210044878	lncRNA gene	Chr5:109239381-109241960 (+)
DBA/2J	ENSMUSG00185055552	lncRNA gene	Chr5:112298368-112300946 (+)
FVB/NJ	ENSMUSG00205052952	lncRNA gene	Chr5:108137905-108140485 (+)
JF1/MsJ	ENSUMUG00000053336	lncRNA gene	Chr5:115115021-115117602 (+)
LP/J	ENSMUSG00230049052	lncRNA gene	Chr5:116387732-116390309 (+)
NOD/ShiLtJ	ENSMUSG00190049271	lncRNA gene	Chr5:108175769-108178348 (+)
NZO/HlLtJ	ENSMUSG00225018002	lncRNA gene	Chr5:124047809-124050386 (+)
PWK/PhJ	ENSLUMG00010040600	lncRNA gene	Chr5:107018751-107021328 (+)
SPRET/EiJ	ENSMSPG00010048154	lncRNA gene	Chr5:110298486-110301072 (+)
WSB/EiJ	ENSIUOG00005044437	lncRNA gene	Chr5:110879572-110882152 (+)

Homology

• Gene Tree
  Hnf1aos2
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  3 involving Hnf1aos2
• Find Mice (IMSR)
  0 strains or lines available

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21

• Ensembl
  ENSMUSG00000086140 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000086140	Ensembl Gene Model | MGI Sequence Detail	2578	C57BL/6J
transcript	ENSMUST00000138108	Ensembl | MGI Sequence Detail	442	Not Applicable

References

• Summaries
  All 11

  Diseases 1

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:332319 Beucher A, et al., The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A. Nat Cell Biol. 2022 Oct;24(10):1528-1540

Hnf1aos2 expression regulated by:

Feature	Feature Type	Location	Reference
Rr124128, regulatory region 124128	promoter	Chr5:115106000-115110601	J:332319

TSS for Hnf1aos2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr48195	Chr5:115106848-115106867 (+)	-24 bp
Tssr48196	Chr5:115106887-115106894 (+)	9 bp
Tssr48197	Chr5:115107929-115107944 (+)	1,055 bp