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Skint8 Gene Detail
Summary
  • Symbol
    Skint8
  • Name
    selection and upkeep of intraepithelial T cells 8
  • Synonyms
    OTTMUSG00000009475
Location &
Maps
more
  • Sequence Map
    Chr4:111776643-111807558 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 51.53 cM
Strain
Comparison
more
  • SNPs within 2kb
    675 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651523
protein coding gene Chr4:111776589-111807558 (+)
129S1/SvImJ ENSMUSG00200044681
protein coding gene Chr4:106838018-106863032 (+)
A/J ENSMUSG00195043288
protein coding gene Chr4:107374439-107399457 (+)
AKR/J ENSMUSG00220011292
protein coding gene Chr4:106702053-106726644 (+)
BALB/cJ ENSMUSG00180045899
protein coding gene Chr4:106197395-106221671 (+)
C3H/HeJ ENSMUSG00175034891
protein coding gene Chr4:107211921-107236216 (+)
C57BL/6NJ ENSMUSG00215023296
protein coding gene Chr4:107145175-107176147 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026294
protein coding gene Chr4:103859673-103947686 (+)
CAST/EiJ ENSTCUG00005021339
protein coding gene Chr4:106199329-106223708 (+)
CBA/J ENSMUSG00210052049
protein coding gene Chr4:106825540-106849818 (+)
DBA/2J ENSMUSG00185048878
protein coding gene Chr4:107534999-107559990 (+)
FVB/NJ ENSMUSG00205021373
protein coding gene Chr4:105694964-105711556 (+)
JF1/MsJ ENSUMUG00000039632
protein coding gene Chr4:107487745-107512242 (+)
LP/J ENSMUSG00230006544
protein coding gene Chr4:110855043-110880035 (+)
NOD/ShiLtJ ENSMUSG00190032566
protein coding gene Chr4:106194985-106219264 (+)
NZO/HlLtJ ENSMUSG00225011019
protein coding gene Chr4:115962365-115993343 (+)
PWK/PhJ ENSLUMG00010041953
protein coding gene Chr4:105209476-105234131 (+)
SPRET/EiJ ENSMSPG00010022875
protein coding gene Chr4:107442902-107467079 (+)
WSB/EiJ ENSIUOG00005036837
protein coding gene Chr4:106437750-106461920 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 639774 NCBI Gene Model | MGI Sequence Detail 30916 C57BL/6J ±  kb
transcript NM_001100466 RefSeq | MGI Sequence Detail 1280 C57BL/6  
polypeptide A7XV07 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:323863 McKenzie DR, et al., Normality sensing licenses local T cells for innate-like tissue surveillance. Nat Immunol. 2022 Mar;23(3):411-422

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory