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Tmem233 Gene Detail
Summary
  • Symbol
    Tmem233
  • Name
    transmembrane protein 233
  • Synonyms
    Gm13843
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651514
    NCBI Gene: 545798
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:116176814-116221303 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 56.10 cM
Strain
Comparison
more
  • SNPs within 2kb
    1806 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651514
 protein coding gene Chr5:116176807-116221326 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029979
 protein coding gene Chr5:118976727-119031776 (-)
A/J MGP_AJ_G0029943
 protein coding gene Chr5:114220414-114265335 (-)
AKR/J MGP_AKRJ_G0029882
 protein coding gene Chr5:117885297-117936127 (-)
BALB/cJ MGP_BALBcJ_G0029954
 protein coding gene Chr5:115622176-115669121 (-)
C3H/HeJ MGP_C3HHeJ_G0029674
 protein coding gene Chr5:118404619-118453039 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030409
 protein coding gene Chr5:123544261-123593547 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027635
 protein coding gene Chr5:108992572-109038253 (-)
CAST/EiJ MGP_CASTEiJ_G0029083
 protein coding gene Chr5:117364443-117413273 (-)
CBA/J MGP_CBAJ_G0029642
 protein coding gene Chr5:128283124-128343987 (-)
DBA/2J MGP_DBA2J_G0029792
 protein coding gene Chr5:114312464-114357907 (-)
FVB/NJ MGP_FVBNJ_G0029748
 protein coding gene Chr5:113137891-113183304 (-)
LP/J MGP_LPJ_G0029880
 protein coding gene Chr5:119533411-119578972 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029779
 protein coding gene Chr5:132579362-132641272 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030450
 protein coding gene Chr5:117367669-117419306 (-)
PWK/PhJ MGP_PWKPhJ_G0028796
 protein coding gene Chr5:112968870-113016478 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028634
 protein coding gene Chr5:114916857-114969209 (-)
WSB/EiJ MGP_WSBEiJ_G0029158
 protein coding gene Chr5:117969428-118020858 (-)



Homology
more
  • Human Ortholog
    TMEM233, transmembrane protein 233
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM233, transmembrane protein 233
  • Synonyms
    DSPB2, IFITMD2
  • Links
    NCBI Gene ID: 387890
    UniProt: B4DJY2

  • Chr Location
    12q24.23; chr12:119593774-119654295 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079278 Ensembl Gene Model | MGI Sequence Detail 44490 C57BL/6J ±  kb
transcript ENSMUST00000111997 Ensembl | MGI Sequence Detail 2477 Not Applicable  
polypeptide ENSMUSP00000107628 Ensembl | MGI Sequence Detail 110 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Primer pair 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:340650 Jami S, et al., Pain-causing stinging nettle toxins target TMEM233 to modulate Na(V)1.7 function. Nat Commun. 2023 Apr 28;14(1):2442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory