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Krtap4-16 Gene Detail
Summary
  • Symbol
    Krtap4-16
  • Name
    keratin associated protein 4-16
  • Synonyms
    OTTMUSG00000002196
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651030
    NCBI Gene: 435285
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99741481-99742431 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 63.19 cM
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651030
protein coding gene Chr11:99741481-99742434 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019123
protein coding gene Chr11:102563662-102564729 (-)
A/J MGP_AJ_G0019093
protein coding gene Chr11:98236492-98237274 (-)
AKR/J MGP_AKRJ_G0019063
protein coding gene Chr11:101284262-101285044 (-)
BALB/cJ MGP_BALBcJ_G0019064
protein coding gene Chr11:98769060-98769843 (-)
C3H/HeJ MGP_C3HHeJ_G0018875
protein coding gene Chr11:101468960-101469799 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019514
protein coding gene Chr11:105689892-105690959 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017143
protein coding gene Chr11:95724782-95725627 (-)
CAST/EiJ MGP_CASTEiJ_G0018429
protein coding gene Chr11:102454172-102455068 (-)
CBA/J MGP_CBAJ_G0018847
protein coding gene Chr11:110129923-110130706 (-)
DBA/2J MGP_DBA2J_G0018957
protein coding gene Chr11:97802688-97803527 (-)
FVB/NJ MGP_FVBNJ_G0018945
protein coding gene Chr11:97318534-97319373 (-)
LP/J MGP_LPJ_G0019026
protein coding gene Chr11:103063614-103064510 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018975
protein coding gene Chr11:109772445-109773398 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019553
protein coding gene Chr11:101652934-101653773 (-)
PWK/PhJ MGP_PWKPhJ_G0018197
protein coding gene Chr11:98853860-98854880 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017985
protein coding gene Chr11:101365905-101366630 (-)
WSB/EiJ MGP_WSBEiJ_G0018480
protein coding gene Chr11:101621326-101622051 (-)



Homology
more
  • Human Ortholog
    KRTAP4-1, keratin associated protein 4-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-1, keratin associated protein 4-1
  • Synonyms
    KAP4.1, KAP4.10, KRTAP4-10, KRTAP4.10
  • Links
    NCBI Gene ID: 85285
    neXtProt AC: NX_Q9BYQ7
    UniProt: Q9BYQ7

  • Chr Location
    17q21.2; chr17:41184100-41184911 (-)  GRCh38

  • Human Ortholog
    KRTAP4-3, keratin associated protein 4-3
  • Synonyms
    KAP4.3
  • Links
    NCBI Gene ID: 85290
    neXtProt AC: NX_Q9BYR4
    UniProt: Q9BYR4

  • Chr Location
    17q21.2; chr17:41167231-41168221 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    3
  • Endonuclease-mediated
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Krtap4-16
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 435285 NCBI Gene Model | MGI Sequence Detail 951 C57BL/6J ±  kb
transcript NM_001013823 RefSeq | MGI Sequence Detail 972 FVB/N  
polypeptide NP_001013845 RefSeq | MGI Sequence Detail 202 FVB/N  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Phenotypes 7
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory