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Pramel23 Gene Detail
Summary
  • Symbol
    Pramel23
  • Name
    PRAME like 23
  • Synonyms
    Gm13089
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649972
    NCBI Gene: 277667
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:143423070-143429281 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 77.88 cM
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649972
 protein coding gene Chr4:143423057-143429281 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0029036
 protein coding gene Chr4:140568247-140574431 (-)
AKR/J MGP_AKRJ_G0028989
 protein coding gene Chr4:144583487-144589680 (-)
BALB/cJ MGP_BALBcJ_G0029056
 protein coding gene Chr4:141224527-141230675 (-)
C3H/HeJ MGP_C3HHeJ_G0028774
 protein coding gene Chr4:144979463-144985675 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029498
 protein coding gene Chr4:151957672-151965111 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0028734
 protein coding gene Chr4:156540709-156546880 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0028852
 protein coding gene Chr4:140039940-140046169 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0028879
 protein coding gene Chr4:160211227-160217476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029539
 protein coding gene Chr4:145131552-145137764 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PRAMEF10, PRAME family member 10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRAMEF10, PRAME family member 10
  • Links
    NCBI Gene ID: 343071
    neXtProt AC: NX_O60809
    UniProt: O60809

  • Chr Location
    1p36.21; chr1:12892896-12898270 (-)  GRCh38
  • Human Ortholog
    PRAMEF2, PRAME family member 2
  • Synonyms
    DJ845O24.3
  • Links
    NCBI Gene ID: 65122
    neXtProt AC: NX_O60811
    UniProt: O60811

  • Chr Location
    1p36.21; chr1:12857086-12861909 (+)  GRCh38
  • Human Ortholog
    PRAMEF33, PRAME family member 33
  • Synonyms
    PRAMEF33P
  • Links
    NCBI Gene ID: 645382
    neXtProt AC: NX_A0A0G2JMD5
    UniProt: A0A0G2JMD5

  • Chr Location
    1p36.21; chr1:13303539-13308907 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PRAME associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070617 Ensembl Gene Model | MGI Sequence Detail 6212 C57BL/6J ±  kb
transcript ENSMUST00000073532 Ensembl | MGI Sequence Detail 1807 Not Applicable  
polypeptide ENSMUSP00000073224 Ensembl | MGI Sequence Detail 455 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR026271 PRAME
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory