Mplkipl1 Gene Detail

Summary

• Symbol
  Mplkipl1
• Name
  M-phase specific PLK1 intereacting protein like 1
• Synonyms
  Gm7102

• Feature Type
  protein coding gene
• IDs
  MGI:3648735
  NCBI Gene: 633057
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr19:61163124-61164747 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 56.79 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  23 from dbSNP Build 142
• Strain Annotations
  9

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648735	protein coding gene	Chr19:61163124-61164747 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020251	protein coding gene	Chr13:14750891-14752728 (+)
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0018244	protein coding gene	Chr13:13095045-13096995 (+)
CAST/EiJ	MGP_CASTEiJ_G0019531	protein coding gene	Chr13:14568069-14570106 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0025230	protein coding gene	Chr19:61612177-61642636 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020100	protein coding gene	Chr13:16293199-16295036 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020665	protein coding gene	Chr13:14568372-14580284 (+)
PWK/PhJ	MGP_PWKPhJ_G0024245	protein coding gene	Chr19:58503404-58504529 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0033662	protein coding gene	Chr9:91865675-91866743 (+)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  MPLKIP, M-phase specific PLK1 interacting protein

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  MPLKIP, M-phase specific PLK1 interacting protein
  
• Synonyms
  ABHS, C7orf11, ORF20, TTD4
• Links
  HGNC:16002

  NCBI Gene ID: 136647

  neXtProt AC: NX_Q8TAP9

  UniProt: Q8TAP9

  
  
• Chr Location
  7p14.1; chr7:40126027-40134622 (-)  GRCh38

---

• MGI Vertebrate Homology
  Mplkipl1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: MPLKIP
• Gene Tree
  Mplkipl1
  

Human Diseases

• Diseases
  1 with human MPLKIP associations

				Human Disease	Mouse Models
				nonphotosensitive trichothiodystrophy 4 IDs nonphotosensitive trichothiodystrophy 4       DOID:0050528 OMIM:234050

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  APF , CvDC
• Find Mice (IMSR)
  33 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  10
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  3

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  18
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS57149.1

• Ensembl
  ENSMUSG00000094649 (Evidence)
• NCBI Gene
  633057

Representative Sequences			Length	Strain/Species
genomic	633057	NCBI Gene Model | MGI Sequence Detail	1624	C57BL/6J
transcript	NM_001177513	RefSeq | MGI Sequence Detail	1624	C57BL/6
polypeptide	NP_001170984	RefSeq | MGI Sequence Detail	178	C57BL/6

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR026618 M-phase-specific PLK1-interacting protein-like, vertebrate
  IPR028265 TTDN1/Protein SICKLE

Molecular
Reagents

• All nucleic 3

  cDNA 3

References

• Summaries
  All 11

  Gene Ontology 2
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;