Sult2a5 MGI Mouse Gene Detail - MGI:3648378 - sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5

Symbol

Sult2a5
Name

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
Synonyms

EG434264, Gm15438

Feature Type

protein coding gene
IDs

MGI:3648378
NCBI Gene: 434264
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr7:13357892-13404732 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 7.96 cM
Mapping Data

1 experiment

SNPs within 2kb

1616 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3648378	protein coding gene	Chr7:13357892-13404732 (+)
129S1/SvImJ	ENSMUSG00200037378	protein coding gene	Chr7:7424379-7471200 (+)
A/J	ENSMUSG00195049372	protein coding gene	Chr7:7084999-7131803 (+)
AKR/J	ENSMUSG00220023426	protein coding gene	Chr7:6569092-6624722 (+)
BALB/cJ	ENSMUSG00180047831	protein coding gene	Chr7:7011025-7057847 (+)
C3H/HeJ	ENSMUSG00175039489	protein coding gene	Chr7:7469357-7516178 (+)
C57BL/6NJ	ENSMUSG00215041200	protein coding gene	Chr7:7706134-7752979 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005024577	protein coding gene	Chr7:7268335-7318349 (+)
CBA/J	ENSMUSG00210035644	protein coding gene	Chr7:6726434-6773261 (+)
DBA/2J	ENSMUSG00185051472	protein coding gene	Chr7:10259104-10305925 (+)
FVB/NJ	ENSMUSG00205037569	protein coding gene	Chr7:7300994-7353065 (+)
JF1/MsJ	ENSUMUG00000048549	protein coding gene	Chr7:9889087-9945841 (+)
LP/J	ENSMUSG00230042383	protein coding gene	Chr7:14441566-14488387 (+)
NOD/ShiLtJ	ENSMUSG00190034549	protein coding gene	Chr7:11339443-11391507 (+)
NZO/HlLtJ	ENSMUSG00225050991	protein coding gene	Chr7:11909516-11956332 (+)
PWK/PhJ	ENSLUMG00010044661	protein coding gene	Chr7:11035005-11084880 (+)
SPRET/EiJ	ENSMSPG00010037869	protein coding gene	Chr7:7256024-7314665 (+)
WSB/EiJ	no annotation

Human Ortholog

SULT2A1, sulfotransferase family 2A member 1

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SULT2A1, sulfotransferase family 2A member 1
Synonyms

DHEAS, DHEA-ST, DHEA-ST8, HST, hSTa, ST2, ST2A1, ST2A3, STD, SULT2A3
Links

HGNC:11458

NCBI Gene ID: 6822

UniProt: Q06520
Chr Location

19q13.33; chr19:47870467-47886347 (-) GRCh38

MGI Vertebrate Homology

Sult2a5 stringent orthology
1 human;1 mouse;3 zebrafish
HCOP

vertebrate homology predictions: SULT2A1
Gene Tree

Sult2a5

Diseases

1 with human SULT2A1 associations

				Human Disease	Mouse Models
				prostate cancer IDs prostate cancer DOID:10283 DOID:514 ICD10CM:C61 ICD9CM:185 KEGG:05215 MESH:D011471 NCI:C3343 NCI:C7378 OMIM:176807 OMIM:300147 OMIM:300704 OMIM:601518 OMIM:602759 OMIM:608656 OMIM:608658 OMIM:609299 OMIM:609558 OMIM:610321 OMIM:610997 OMIM:611100 OMIM:611868 OMIM:611928 OMIM:611955 OMIM:611958 OMIM:611959 ORDO:1331 UMLS_CUI:C0033578 UMLS_CUI:C0376358

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

3 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

2
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

18 strains or lines available

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All GO Annotations

22
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

3

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

26
RefSeq

2
UniProt

1
CCDS

CCDS52029.1

Ensembl

ENSMUSG00000078799 (Evidence)
NCBI Gene

434264

			Length	Strain/Species	Flank
genomic	434264	NCBI Gene Model \| MGI Sequence Detail	46841	C57BL/6J	± kb
transcript	NM_001184980	RefSeq \| MGI Sequence Detail	1046	C57BL/6
polypeptide	NP_001171909	RefSeq \| MGI Sequence Detail	285	C57BL/6

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UniProt

1 Sequence
EC

2.8.2.-
InterPro Domains

IPR027417 P-loop containing nucleoside triphosphate hydrolase

IPR000863 Sulfotransferase domain

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All nucleic 3

cDNA 3

Summaries

All 18

Gene Ontology 5

Phenotypes 3
Earliest

J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
Latest

J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;

TSS for Sult2a5:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr64553	Chr7:13357898-13357907 (+)	11 bp
Tssr64554	Chr7:13357908-13357926 (+)	25 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/08/2026 MGI 6.24