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Slc38a6 Gene Detail
Summary
  • Symbol
    Slc38a6
  • Name
    solute carrier family 38, member 6
  • Synonyms
    EG625098
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648156
    NCBI Gene: 625098
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:73333553-73400823 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 30.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    488 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648156
 protein coding gene Chr12:73333553-73408772 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019836
 protein coding gene Chr12:73182205-73250156 (+)
A/J MGP_AJ_G0019794
 protein coding gene Chr12:70445760-70511656 (+)
AKR/J MGP_AKRJ_G0019769
 protein coding gene Chr12:72580664-72644843 (+)
BALB/cJ MGP_BALBcJ_G0019774
 protein coding gene Chr12:70925872-70989555 (+)
C3H/HeJ MGP_C3HHeJ_G0019579
 protein coding gene Chr12:73010995-73080097 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020226
 protein coding gene Chr12:75460203-75531671 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017844
 protein coding gene Chr12:67888657-67951891 (+)
CAST/EiJ MGP_CASTEiJ_G0019131
 protein coding gene Chr12:67808345-67879402 (+)
CBA/J MGP_CBAJ_G0019549
 protein coding gene Chr12:78336238-78413232 (+)
DBA/2J MGP_DBA2J_G0019665
 protein coding gene Chr12:70340617-70403290 (+)
FVB/NJ MGP_FVBNJ_G0019652
 protein coding gene Chr12:69188738-69251458 (+)
LP/J MGP_LPJ_G0019737
 protein coding gene Chr12:73206528-73269007 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019691
 protein coding gene Chr12:81470530-81538217 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020261
 protein coding gene Chr12:72065986-72133809 (+)
PWK/PhJ MGP_PWKPhJ_G0018896
 protein coding gene Chr12:64659007-64749777 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018691
 protein coding gene Chr12:66489015-66558759 (+)
WSB/EiJ MGP_WSBEiJ_G0019182
 protein coding gene Chr12:72656934-72723601 (+)



Homology
more
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC38A6, solute carrier family 38 member 6
  • Synonyms
    NAT-1, SNAT6
  • Links
    NCBI Gene ID: 145389
    neXtProt AC: NX_Q8IZM9
    UniProt: Q8IZM9

  • Chr Location
    14q23.1; chr14:60981114-61114316 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    8
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044712 Ensembl Gene Model | MGI Sequence Detail 67271 C57BL/6J ±  kb
transcript ENSMUST00000140523 Ensembl | MGI Sequence Detail 3032 Not Applicable  
polypeptide ENSMUSP00000120810 Ensembl | MGI Sequence Detail 457 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145022
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:344978 Peng Y, et al., SLC38A6 expression in macrophages exacerbates pulmonary inflammation. Respir Res. 2023 Jan 27;24(1):33
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory