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Plcxd2 Gene Detail
Summary
  • Symbol
    Plcxd2
  • Name
    phosphatidylinositol-specific phospholipase C, X domain containing 2
  • Synonyms
    EG433022
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647874
    NCBI Gene: 433022
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:45779626-45830581 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 30.45 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    413 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647874
 protein coding gene Chr16:45779624-45830776 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022860
 protein coding gene Chr16:44765404-44821618 (-)
A/J MGP_AJ_G0022825
 protein coding gene Chr16:42766515-42819818 (-)
AKR/J MGP_AKRJ_G0022797
 protein coding gene Chr16:44163349-44214110 (-)
BALB/cJ MGP_BALBcJ_G0022826
 protein coding gene Chr16:42785989-42838414 (-)
C3H/HeJ MGP_C3HHeJ_G0022590
 protein coding gene Chr16:44319994-44376267 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023273
 protein coding gene Chr16:45786976-45839818 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020787
 protein coding gene Chr16:43119806-43173393 (-)
CAST/EiJ MGP_CASTEiJ_G0022115
 protein coding gene Chr16:44526359-44580488 (-)
CBA/J MGP_CBAJ_G0022561
 protein coding gene Chr16:47698735-47754517 (-)
DBA/2J MGP_DBA2J_G0022693
 protein coding gene Chr16:42498915-42550047 (-)
FVB/NJ MGP_FVBNJ_G0022669
 protein coding gene Chr16:42411199-42464055 (-)
LP/J MGP_LPJ_G0022761
 protein coding gene Chr16:44518081-44573515 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022687
 protein coding gene Chr16:47108589-47161473 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023288
 protein coding gene Chr16:44183211-44233648 (-)
PWK/PhJ MGP_PWKPhJ_G0021855
 protein coding gene Chr16:42873143-42924329 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021686
 protein coding gene Chr16:44111359-44162650 (-)
WSB/EiJ MGP_WSBEiJ_G0022160
 protein coding gene Chr16:44276592-44328834 (-)



Homology
more
  • Human Ortholog
    PLCXD2, phosphatidylinositol specific phospholipase C X domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLCXD2, phosphatidylinositol specific phospholipase C X domain containing 2
  • Links
    NCBI Gene ID: 257068
    neXtProt AC: NX_Q0VAA5
    UniProt: Q0VAA5

  • Chr Location
    3q13.2; chr3:111674676-111846447 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    979
  • Tissues
    150
  • cDNA Data
    9
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000087141 Ensembl Gene Model | MGI Sequence Detail 50956 C57BL/6J ±  kb
transcript ENSMUST00000130481 Ensembl | MGI Sequence Detail 7140 Not Applicable  
polypeptide ENSMUSP00000114852 Ensembl | MGI Sequence Detail 340 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029685 PI-PLC X domain-containing protein 2
    (term hierarchy)
  • InterPro Domains
    IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
    IPR042158 PI-PLC X domain-containing protein 1/2/3
    IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146646
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory