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Tmem178b Gene Detail
Summary
  • Symbol
    Tmem178b
  • Name
    transmembrane protein 178B
  • Synonyms
    A930009E05Rik, Gm5567
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647581
    NCBI Gene: 434008
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:39848395-40232084 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 18.82 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    9214 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647581
 protein coding gene Chr6:39848164-40232084 (+)
129S1/SvImJ ENSMUSG00200045464
 protein coding gene Chr6:36903935-37287572 (+)
A/J ENSMUSG00195041662
 protein coding gene Chr6:36875704-37259376 (+)
AKR/J ENSMUSG00220006197
 protein coding gene Chr6:36474376-36858060 (+)
BALB/cJ ENSMUSG00180041404
 protein coding gene Chr6:37004177-37387806 (+)
C3H/HeJ ENSMUSG00175038421
 protein coding gene Chr6:36831326-37214972 (+)
C57BL/6NJ ENSMUSG00215046557
 protein coding gene Chr6:36910440-37294092 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028253
 protein coding gene Chr6:34502640-34873105 (+)
CAST/EiJ ENSTCUG00005024682
 protein coding gene Chr6:36410127-36792537 (+)
CBA/J ENSMUSG00210051759
 protein coding gene Chr6:36883126-37266770 (+)
DBA/2J ENSMUSG00185047703
 protein coding gene Chr6:36985598-37369245 (+)
FVB/NJ ENSMUSG00205047967
 protein coding gene Chr6:36968536-37345298 (+)
JF1/MsJ ENSUMUG00000017455
 protein coding gene Chr6:36640067-37022603 (+)
LP/J ENSMUSG00230038641
 protein coding gene Chr6:37909376-38292994 (+)
NOD/ShiLtJ ENSMUSG00190046771
 protein coding gene Chr6:36750002-37133643 (+)
NZO/HlLtJ ENSMUSG00225008108
 protein coding gene Chr6:39891985-40275623 (+)
PWK/PhJ ENSLUMG00010038634
 protein coding gene Chr6:36413022-36802166 (+)
SPRET/EiJ ENSMSPG00010022658
 protein coding gene Chr6:37024603-37418129 (+)
WSB/EiJ ENSIUOG00005028078
 protein coding gene Chr6:37084702-37468517 (+)



Homology
more
  • Human Ortholog
    TMEM178B, transmembrane protein 178B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM178B, transmembrane protein 178B
  • Links
    NCBI Gene ID: 100507421
    UniProt: H3BS89

  • Chr Location
    chr7:141074064-141511296 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    7
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000057716 Ensembl Gene Model | MGI Sequence Detail 383690 C57BL/6J ±  kb
    transcript ENSMUST00000239008 Ensembl | MGI Sequence Detail 2495 Not Applicable  
    polypeptide ENSMUSP00000159180 Ensembl | MGI Sequence Detail 294 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR004031 PMP-22/EMP/MP20/Claudin
      IPR039625 Transmembrane protein 178A/B
    • GlyGen
      A0A5F8MQ13 3 sites, 3 N-linked glycans (3 sites)
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 7
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1925046
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory