Gm8458 Pseudogene Detail

Summary

• Symbol
  Gm8458
• Name
  predicted gene 8458

• Feature Type
  pseudogene
• IDs
  MGI:3647455
  NCBI Gene: 667104
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr5:146007716-146008534 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 85.17 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  201 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3647455	pseudogene	Chr5:146007716-146008534 (+)
129S1/SvImJ	ENSMUSG00200041862	pseudogene	Chr5:139836627-139837445 (+)
A/J	ENSMUSG00195045734	pseudogene	Chr5:139366213-139367031 (+)
AKR/J	ENSMUSG00220023595	pseudogene	Chr5:138457366-138458184 (+)
BALB/cJ	ENSMUSG00180035420	pseudogene	Chr5:139711618-139712436 (+)
C3H/HeJ	ENSMUSG00175049006	pseudogene	Chr5:141638422-141639240 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005037379	pseudogene	Chr5:138883647-138884411 (+)
CBA/J	ENSMUSG00210024610	pseudogene	Chr5:140590946-140591764 (+)
DBA/2J	ENSMUSG00185041574	pseudogene	Chr5:143441155-143441973 (+)
FVB/NJ	no annotation
JF1/MsJ	ENSUMUG00000051945	pseudogene	Chr5:146020484-146021324 (+)
LP/J	ENSMUSG00230030903	pseudogene	Chr5:147553622-147554440 (+)
NOD/ShiLtJ	ENSMUSG00190046381	pseudogene	Chr5:139168954-139169772 (+)
NZO/HlLtJ	ENSMUSG00225008984	pseudogene	Chr5:155169492-155170310 (+)
PWK/PhJ	ENSLUMG00010021196	pseudogene	Chr5:138323192-138324022 (+)
SPRET/EiJ	no annotation
WSB/EiJ	ENSIUOG00005038407	pseudogene	Chr5:141947476-141948294 (+)

Homology

• Gene Tree
  Gm8458
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  19 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Genomic Mutations
  4 involving Gm8458
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  19
• RefSeq
  1

• Ensembl
  ENSMUSG00000105390 (Evidence)
• NCBI Gene
  667104

Representative Sequences			Length	Strain/Species
genomic	667104	NCBI Gene Model | MGI Sequence Detail	819	C57BL/6J

References

• Summaries
  All 24

  Phenotypes 19
• Earliest
  J:127366 van Herwaarden AE, et al., Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J Clin Invest. 2007 Nov;117(11):3583-92
• Latest
  J:387287 Stromatt JC, et al., Drug-Drug Interaction Liabilities with BTK Inhibitor TL-895. Cancer Res Commun. 2025 Sep 1;5(9):1621-1630