Gbp2-ps Pseudogene Detail

Summary

• Symbol
  Gbp2-ps
• Name
  guanylate binding protein 2, pseudogene
• Synonyms
  Gm6243

• Feature Type
  pseudogene
• IDs
  MGI:3647028
  NCBI Gene: 621605
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr3:142364712-142369269 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 66.69 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  358 from dbSNP Build 142
• Strain Annotations
  19

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3647028	pseudogene	Chr3:142364709-142375144 (+)
129S1/SvImJ	ENSMUSG00200003396	pseudogene	Chr3:139178959-139189359 (+)
A/J	ENSMUSG00195004546	pseudogene	Chr3:139355381-139365781 (+)
AKR/J	ENSMUSG00220003953	pseudogene	Chr3:137749149-137759457 (+)
BALB/cJ	ENSMUSG00180012343	pseudogene	Chr3:139226011-139236409 (+)
C3H/HeJ	ENSMUSG00175020391	pseudogene	Chr3:138809500-138819898 (+)
C57BL/6NJ	ENSMUSG00215027372	pseudogene	Chr3:139547599-139558033 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0037329	pseudogene	Chr3:135913214-135917471 (+)
CAST/EiJ	ENSTCUG00005031096	pseudogene	Chr3:139964040-139974318 (+)
CBA/J	ENSMUSG00210033237	pseudogene	Chr3:139495264-139505449 (+)
DBA/2J	ENSMUSG00185003734	pseudogene	Chr3:140075731-140086044 (+)
FVB/NJ	ENSMUSG00205026918	pseudogene	Chr3:138371096-138381409 (+)
JF1/MsJ	ENSUMUG00000005625	pseudogene	Chr3:138895704-138905898 (+)
LP/J	ENSMUSG00230003820	pseudogene	Chr3:141991707-142002105 (+)
NOD/ShiLtJ	ENSMUSG00190004986	pseudogene	Chr3:140442943-140453252 (+)
NZO/HlLtJ	ENSMUSG00225003204	pseudogene	Chr3:144492943-144503252 (+)
PWK/PhJ	ENSLUMG00010022345	pseudogene	Chr3:138795883-138802533 (+)
SPRET/EiJ	ENSMSPG00010014925	pseudogene	Chr3:140048560-140058876 (+)
WSB/EiJ	ENSIUOG00005019163	pseudogene	Chr3:139600769-139611176 (+)

Homology

• Gene Tree
  Gbp2-ps
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from multigenic genotypes
  31 phenotype references
  

• All Mutations and Alleles
  3
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  2 involving Gbp2-ps
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  23
• RefSeq
  1

• Ensembl
  ENSMUSG00000105317 (Evidence)
• NCBI Gene
  621605

Representative Sequences			Length	Strain/Species
genomic	621605	NCBI Gene Model | MGI Sequence Detail	4558	C57BL/6J

References

• Summaries
  All 36

  Diseases 1

  Phenotypes 31
• Earliest
  J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
• Latest
  J:382922 Pizzuto M, et al., Cardiolipin inhibits the non-canonical inflammasome by preventing LPS binding to caspase-4/11. EMBO J. 2025 Aug;44(16):4419-4442