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Fbxw26 Gene Detail
Summary
  • Symbol
    Fbxw26
  • Name
    F-box and WD-40 domain protein 26
  • Synonyms
    Gm5163
Location &
Maps
more
  • Sequence Map
    Chr9:109546634-109575157 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    915 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646662
 protein coding gene Chr9:109546634-109575157 (-)
129S1/SvImJ ENSMUSG00200040396
 protein coding gene Chr9:106639822-106668385 (-)
A/J ENSMUSG00195043775
 protein coding gene Chr9:105932178-105960733 (-)
AKR/J ENSMUSG00220026269
 protein coding gene Chr9:106267923-106296469 (-)
BALB/cJ ENSMUSG00180033857
 protein coding gene Chr9:106387116-106415679 (-)
C3H/HeJ ENSMUSG00175032897
 protein coding gene Chr9:106602991-106631554 (-)
C57BL/6NJ ENSMUSG00215026997
 protein coding gene Chr9:106483313-106511840 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005025168
 protein coding gene Chr9:106304377-106332947 (-)
CBA/J ENSMUSG00210030640
 protein coding gene Chr9:106318734-106347016 (-)
DBA/2J ENSMUSG00185040967
 protein coding gene Chr9:106650988-106679545 (-)
FVB/NJ ENSMUSG00205047199
 protein coding gene Chr9:106583060-106611649 (-)
JF1/MsJ ENSUMUG00000027795
 protein coding gene Chr9:106420934-106449220 (-)
LP/J ENSMUSG00230047144
 protein coding gene Chr9:106772030-106800601 (-)
NOD/ShiLtJ ENSMUSG00190036397
 protein coding gene Chr9:106238641-106267195 (-)
NZO/HlLtJ ENSMUSG00225023745
 protein coding gene Chr9:107021481-107050036 (-)
PWK/PhJ ENSLUMG00010035600
 protein coding gene Chr9:106436277-106464552 (-)
SPRET/EiJ ENSMSPG00010043726
 protein coding gene Chr9:108200337-108237712 (-)
WSB/EiJ ENSIUOG00005045440
 protein coding gene Chr9:105697190-105725697 (-)



Homology
more
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Synonyms
    FBW12, FBXO12, FBXO35
  • Links
    NCBI Gene ID: 285231
    UniProt: Q6X9E4

  • Chr Location
    3p21.31; chr3:48372219-48401259 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 382109 NCBI Gene Model | MGI Sequence Detail 28524 C57BL/6J ±  kb
transcript NM_198674 RefSeq | MGI Sequence Detail 1824 C57BL/6  
polypeptide NP_941076 RefSeq | MGI Sequence Detail 466 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001810 F-box domain
    IPR036047 F-box-like domain superfamily
    IPR052121 F-box Protein Family Substrate Recognition Components
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Phenotypes 9
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory