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Defb51 Gene Detail
Summary
  • Symbol
    Defb51
  • Name
    defensin beta 51
  • Synonyms
    Gm6040
Location &
Maps
more
  • Sequence Map
    Chr8:21406506-21412087 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 10.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    254 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646527
 protein coding gene Chr8:21391976-21412114 (-)
129S1/SvImJ ENSMUSG00200030858
 protein coding gene Chr8:16536020-16541604 (-)
A/J ENSMUSG00195039299
 protein coding gene Chr8:17075477-17081062 (-)
AKR/J ENSMUSG00220028486
 protein coding gene Chr8:17215171-17220756 (-)
BALB/cJ ENSMUSG00180022401
 protein coding gene Chr8:16616636-16622220 (-)
C3H/HeJ ENSMUSG00175037559
 protein coding gene Chr8:16756790-16762374 (-)
C57BL/6NJ ENSMUSG00215014089
 protein coding gene Chr8:16731580-16737162 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030879
 protein coding gene Chr8:15459119-15464990 (-)
CAST/EiJ ENSTCUG00005018433
 protein coding gene Chr8:16986356-16991946 (-)
CBA/J ENSMUSG00210040114
 protein coding gene Chr8:16616091-16621675 (-)
DBA/2J ENSMUSG00185038868
 protein coding gene Chr8:22419004-22424588 (-)
FVB/NJ ENSMUSG00205026520
 protein coding gene Chr8:16329444-16335029 (-)
JF1/MsJ ENSUMUG00000012933
 protein coding gene Chr8:24599042-24604621 (-)
LP/J ENSMUSG00230011401
 protein coding gene Chr8:26318821-26324404 (-)
NOD/ShiLtJ ENSMUSG00190031907
 protein coding gene Chr8:16752018-16757603 (-)
NZO/HlLtJ ENSMUSG00225041557
 protein coding gene Chr8:29670850-29676431 (-)
PWK/PhJ ENSLUMG00010026727
 protein coding gene Chr8:17006499-17012077 (-)
SPRET/EiJ ENSMSPG00010013864
 protein coding gene Chr8:17060501-17065745 (-)
WSB/EiJ ENSIUOG00005020820
 protein coding gene Chr8:17238434-17244021 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071165 Ensembl Gene Model | MGI Sequence Detail 5582 C57BL/6J ±  kb
transcript ENSMUST00000095430 Ensembl | MGI Sequence Detail 857 Not Applicable  
polypeptide ENSMUSP00000093080 Ensembl | MGI Sequence Detail 63 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:8352884
References
more
  • Summaries
    All 14
    Phenotypes 1
  • Earliest
    J:101568 Patil AA, et al., Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol Genomics. 2005 Sep 21;23(1):5-17
  • Latest
    J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory