Ceacam3 MGI Mouse Gene Detail - MGI:3646296 - CEA cell adhesion molecule 3

Symbol

Ceacam3
Name

CEA cell adhesion molecule 3
Synonyms

cea12, EG384557, Psg24

Feature Type

protein coding gene
IDs

MGI:3646296
NCBI Gene: 384557
Member of

Cea cluster
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr7:16884207-16898178 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 9.15 cM, cytoband A2
Mapping Data

2 experiments

SNPs within 2kb

212 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3646296	protein coding gene	Chr7:16884122-16898891 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031730	protein coding gene	Chr7:14930603-14947558 (+)
A/J	MGP_AJ_G0031702	protein coding gene	Chr7:14641856-14657034 (+)
AKR/J	MGP_AKRJ_G0031627	protein coding gene	Chr7:14984493-15000627 (+)
BALB/cJ	MGP_BALBcJ_G0031709	protein coding gene	Chr7:14760464-14776402 (+)
C3H/HeJ	MGP_C3HHeJ_G0031431	protein coding gene	Chr7:15170788-15207921 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032175	protein coding gene	Chr7:15646461-15663698 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029255	protein coding gene	Chr7:16168707-16182320 (+)
CAST/EiJ	MGP_CASTEiJ_G0030782	protein coding gene	Chr7:11936390-11953273 (+)
CBA/J	MGP_CBAJ_G0031390	protein coding gene	Chr7:16200830-16228483 (+)
DBA/2J	MGP_DBA2J_G0031546	protein coding gene	Chr7:14524274-14538413 (+)
FVB/NJ	MGP_FVBNJ_G0031502	protein coding gene	Chr7:14434109-14448410 (+)
LP/J	MGP_LPJ_G0031631	protein coding gene	Chr7:15173876-15187657 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031537	protein coding gene	Chr7:16110758-16127360 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032204	protein coding gene	Chr7:14770185-14784704 (+)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0030333	protein coding gene	Chr7:9672757-9686473 (+)
WSB/EiJ	MGP_WSBEiJ_G0030879	protein coding gene	Chr7:14828214-14855878 (+)

Human Ortholog

CEACAM7, CEA cell adhesion molecule 7

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CEACAM7, CEA cell adhesion molecule 7
Synonyms

CGM2
Links

HGNC:1819

NCBI Gene ID: 1087

neXtProt AC: NX_Q14002

UniProt: Q14002
Chr Location

19q13.2; chr19:41673307-41688277 (-) GRCh38.p7

Alliance of Genome Resources

Ceacam3 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CEACAM7
Gene Tree

Ceacam3

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
5 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Endonuclease-mediated

2
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

21 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

5
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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Ceacam3 interacts with 197 markers (Mir1a-1, Mir1a-2, Mir7-2, ...) View All

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All Sequences

31
RefSeq

8
UniProt

1
CCDS

CCDS57499.1

Ensembl

ENSMUSG00000053228 (Evidence)
NCBI Gene

384557

			Length	Strain/Species	Flank
genomic	ENSMUSG00000053228	Ensembl Gene Model \| MGI Sequence Detail	13972	C57BL/6J	± kb
transcript	ENSMUST00000108491	Ensembl \| MGI Sequence Detail	3261	Not Applicable
polypeptide	ENSMUSP00000104131	Ensembl \| MGI Sequence Detail	706	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR013151 Immunoglobulin

IPR007110 Immunoglobulin-like domain

IPR036179 Immunoglobulin-like domain superfamily

IPR013783 Immunoglobulin-like fold

IPR003599 Immunoglobulin subtype

IPR003598 Immunoglobulin subtype 2

IPR013106 Immunoglobulin V-set domain

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All nucleic 1

cDNA 1

Microarray probesets 1

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MGI:1891356

Summaries

All 21

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 5
Earliest

J:98494 McLellan AS, et al., Structure and evolution of the mouse pregnancy-specific glycoprotein (Psg) gene locus. BMC Genomics. 2005 Jan 12;6(1):4
Latest

J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Ceacam3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr64690	Chr7:16884116-16884123 (+)	-87 bp
Tssr64691	Chr7:16884135-16884161 (+)	-59 bp
Tssr64692	Chr7:16884172-16884177 (+)	-32 bp
Tssr64693	Chr7:16884195-16884200 (+)	-9 bp
Tssr64694	Chr7:16884290-16884299 (+)	88 bp
Tssr64695	Chr7:16897184-16897208 (+)	12,989 bp
Tssr64696	Chr7:16897288-16897297 (+)	13,086 bp
Tssr64697	Chr7:16897618-16897627 (+)	13,416 bp
Tssr64698	Chr7:16897633-16897645 (+)	13,432 bp
Tssr64699	Chr7:16897881-16897886 (+)	13,677 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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