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Cstdc4 Gene Detail
Summary
  • Symbol
    Cstdc4
  • Name
    cystatin domain containing 4
  • Synonyms
    Gm5483
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645124
    NCBI Gene: 433016
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:36004582-36008481 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 25.43 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    249 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645124
protein coding gene Chr16:36004582-36008481 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022782
protein coding gene Chr16:34576838-34580693 (+)
A/J MGP_AJ_G0022747
protein coding gene Chr16:32882648-32886501 (+)
AKR/J MGP_AKRJ_G0022723
protein coding gene Chr16:34121630-34126695 (+)
BALB/cJ MGP_BALBcJ_G0022748
protein coding gene Chr16:33020153-33024028 (+)
C3H/HeJ MGP_C3HHeJ_G0022513
protein coding gene Chr16:34215821-34219696 (+)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0022482
protein coding gene Chr16:36810687-36820890 (+)
DBA/2J MGP_DBA2J_G0022616
protein coding gene Chr16:32719147-32723014 (+)
FVB/NJ MGP_FVBNJ_G0022592
protein coding gene Chr16:32711423-32715294 (+)
LP/J MGP_LPJ_G0022683
protein coding gene Chr16:34310965-34314836 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022611
protein coding gene Chr16:36012137-36016010 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023210
protein coding gene Chr16:34105537-34109408 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CSTA, cystatin A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSTA, cystatin A
  • Synonyms
    AREI, PSS4, STF1, STFA
  • Links
    NCBI Gene ID: 1475
    neXtProt AC: NX_P01040
    UniProt: P01040

  • Chr Location
    3q21.1; chr3:122325248-122341969 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human CSTA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 433016 NCBI Gene Model | MGI Sequence Detail 3900 C57BL/6J ±  kb
transcript NM_001082547 RefSeq | MGI Sequence Detail 414 C57BL/6  
polypeptide NP_001076016 RefSeq | MGI Sequence Detail 97 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR000010 Cystatin domain
    IPR046350 Cystatin superfamily
    IPR001713 Proteinase inhibitor I25A, stefin
    IPR018073 Proteinase inhibitor I25, cystatin, conserved site
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
Other
Accession IDs
less
MGI:6275074
References
more
  • Summaries
    All 10
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:293217 GemPharmatech, GemPharmatech Website. 2020;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory