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Cyp2ab1 Gene Detail
Summary
  • Symbol
    Cyp2ab1
  • Name
    cytochrome P450, family 2, subfamily ab, polypeptide 1
  • Synonyms
    EG224044
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644957
    NCBI Gene: 224044
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:20127137-20144154 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 12.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    547 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644957
 protein coding gene Chr16:20127137-20144154 (-)
129S1/SvImJ ENSMUSG00200044559
 protein coding gene Chr16:17124485-17141505 (-)
A/J ENSMUSG00195028134
 protein coding gene Chr16:16682039-16699054 (-)
AKR/J ENSMUSG00220036954
 protein coding gene Chr16:16999691-17016711 (-)
BALB/cJ ENSMUSG00180035357
 protein coding gene Chr16:16923273-16940290 (-)
C3H/HeJ ENSMUSG00175044449
 protein coding gene Chr16:17068338-17085355 (-)
C57BL/6NJ ENSMUSG00215029559
 protein coding gene Chr16:16789276-16806293 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020574
 protein coding gene Chr16:17466601-17482296 (-)
CAST/EiJ ENSTCUG00005040365
 protein coding gene Chr16:17406118-17423121 (-)
CBA/J ENSMUSG00210040861
 protein coding gene Chr16:17090132-17107149 (-)
DBA/2J ENSMUSG00185029944
 protein coding gene Chr16:17028873-17045890 (-)
FVB/NJ ENSMUSG00205039110
 protein coding gene Chr16:17031355-17048373 (-)
JF1/MsJ ENSUMUG00000022611
 protein coding gene Chr16:17209590-17226740 (-)
LP/J ENSMUSG00230044230
 protein coding gene Chr16:19608141-19625158 (-)
NOD/ShiLtJ ENSMUSG00190033122
 protein coding gene Chr16:17170394-17187411 (-)
NZO/HlLtJ ENSMUSG00225036340
 protein coding gene Chr16:22853934-22870951 (-)
PWK/PhJ ENSLUMG00010046642
 protein coding gene Chr16:17033833-17051317 (-)
SPRET/EiJ ENSMSPG00010045019
 protein coding gene Chr16:16911447-16918901 (-)
WSB/EiJ ENSIUOG00005042943
 protein coding gene Chr16:17225685-17242703 (-)



Homology
more
  • Human Ortholog
    CYP2AB1P, cytochrome P450 family 2 subfamily AB member 1, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2AB1P, cytochrome P450 family 2 subfamily AB member 1, pseudogene
  • Links
    NCBI Gene ID: 647265

  • Chr Location
    3q27.1; chr3:183895164-183910936 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    9
  • cDNA Data
    1
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 224044 NCBI Gene Model | MGI Sequence Detail 17018 C57BL/6J ±  kb
    transcript NM_183158 RefSeq | MGI Sequence Detail 2735 C57BL/6  
    polypeptide NP_898981 RefSeq | MGI Sequence Detail 280 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 3
      Genomic 2
      cDNA 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory