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Sgo2b Gene Detail
Summary
  • Symbol
    Sgo2b
  • Name
    shugoshin 2B
  • Synonyms
    Gm4975, Sgol2b
Location &
Maps
more
  • Sequence Map
    Chr8:64377728-64405204 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 32.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1319 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644562
 protein coding gene Chr8:64360461-64405204 (-)
129S1/SvImJ ENSMUSG00200007324
 protein coding gene Chr8:59209827-59237309 (-)
A/J ENSMUSG00195012127
 protein coding gene Chr8:59553053-59580565 (-)
AKR/J ENSMUSG00220005156
 protein coding gene Chr8:59396275-59419702 (-)
BALB/cJ ENSMUSG00180013893
 protein coding gene Chr8:59189572-59212994 (-)
C3H/HeJ ENSMUSG00175007335
 protein coding gene Chr8:59414453-59437879 (-)
C57BL/6NJ ENSMUSG00215007053
 protein coding gene Chr8:59200281-59227762 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014157
 protein coding gene Chr1:51762158-51783445 (+)
CAST/EiJ ENSTCUG00005006455
 protein coding gene Chr8:59033286-59060414 (-)
CBA/J ENSMUSG00210008931
 protein coding gene Chr8:59295456-59318880 (-)
DBA/2J ENSMUSG00185022102
 protein coding gene Chr8:65348899-65372320 (-)
FVB/NJ ENSMUSG00205010190
 protein coding gene Chr8:58626967-58654455 (-)
JF1/MsJ ENSUMUG00000007433
 protein coding gene Chr8:67614320-67641061 (-)
LP/J ENSMUSG00230006186
 protein coding gene Chr8:69007017-69030438 (-)
NOD/ShiLtJ ENSMUSG00190009452
 protein coding gene Chr8:59159202-59186713 (-)
NZO/HlLtJ ENSMUSG00225045490
 protein coding gene Chr8:72433429-72458278 (-)
PWK/PhJ ENSLUMG00010012772
 protein coding gene Chr8:59087996-59114641 (-)
SPRET/EiJ ENSMSPG00010014145
 protein coding gene Chr8:60321221-60347961 (-)
WSB/EiJ ENSIUOG00005016603
 protein coding gene Chr8:60108488-60135916 (-)



Homology
more
  • Human Ortholog
    SGO2, shugoshin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SGO2, shugoshin 2
  • Synonyms
    SGOL2, TRIPIN
  • Links
    NCBI Gene ID: 151246
    UniProt: Q562F6

  • Chr Location
    2q33.1; chr2:200510008-200584096 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Sgo2b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    34 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 244495 NCBI Gene Model | MGI Sequence Detail 27477 C57BL/6J ±  kb
transcript NM_001195687 RefSeq | MGI Sequence Detail 3739 C57BL/6  
polypeptide NP_001182616 RefSeq | MGI Sequence Detail 1167 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR038889 Shugoshin 1/2
  • GlyGen
    J3QMK1 3 sites, 3 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:5892221
References
more
  • Summaries
    All 19
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory