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Sfta2 Gene Detail
Summary
  • Symbol
    Sfta2
  • Name
    surfactant associated 2
  • Synonyms
    EG433102
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643293
    NCBI Gene: 433102
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35960600-35961461 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 17, 18.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643293
protein coding gene Chr17:35912441-35961463 (+)
129S1/SvImJ ENSMUSG00200049449
protein coding gene Chr17:31529347-31592472 (+)
A/J ENSMUSG00195044593
protein coding gene Chr17:32605742-32655515 (+)
AKR/J ENSMUSG00220037464
protein coding gene Chr17:31392893-31455997 (+)
BALB/cJ ENSMUSG00180031622
protein coding gene Chr17:31975533-32025301 (+)
C3H/HeJ ENSMUSG00175037129
protein coding gene Chr17:31278706-31341811 (+)
C57BL/6NJ ENSMUSG00215052336
protein coding gene Chr17:31362943-31411970 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021526
protein coding gene Chr17:32380604-32427098 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210047354
protein coding gene Chr17:31100792-31163886 (+)
DBA/2J ENSMUSG00185043090
protein coding gene Chr17:33994705-34044476 (+)
FVB/NJ ENSMUSG00205053223
protein coding gene Chr17:31658498-31705993 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230054468
protein coding gene Chr17:35018055-35081165 (+)
NOD/ShiLtJ ENSMUSG00190040031
protein coding gene Chr17:31277666-31325149 (+)
NZO/HlLtJ ENSMUSG00225051131
protein coding gene Chr17:37094759-37157883 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SFTA2, surfactant associated 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SFTA2, surfactant associated 2
  • Synonyms
    GSGL541, SFTPG, SP-G, UNQ541
  • Links
    NCBI Gene ID: 389376
    UniProt: Q6UW10

  • Chr Location
    6p21.33; chr6:30931353-30955636 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 433102 NCBI Gene Model | MGI Sequence Detail 862 C57BL/6J ±  kb
transcript NM_001163194 RefSeq | MGI Sequence Detail 506 C57BL/6  
polypeptide E9PXB6 UniProt | EBI | MGI Sequence Detail 77 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 20
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:324105 Meinicke A, et al., Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content. Biomolecules. 2022 Jan 7;12(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory