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Phldb3 Gene Detail
Summary
  • Symbol
    Phldb3
  • Name
    pleckstrin homology like domain, family B, member 3
  • Synonyms
    EG232970, Gm10102
  • Feature Type
    protein coding gene
  • IDs
    MGI:3642959
    NCBI Gene: 232970
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:24310188-24328722 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 11.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    554 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642959
 protein coding gene Chr7:24309731-24328722 (+)
129S1/SvImJ ENSMUSG00200037829
 protein coding gene Chr7:14313220-14331757 (+)
A/J ENSMUSG00195050272
 protein coding gene Chr7:16749984-16768520 (+)
AKR/J ENSMUSG00220044884
 protein coding gene Chr7:27622063-27640600 (-)
BALB/cJ ENSMUSG00180053668
 protein coding gene Chr7:14821965-14840505 (+)
C3H/HeJ ENSMUSG00175050239
 protein coding gene Chr7:15866166-15884702 (+)
C57BL/6NJ ENSMUSG00215053148
 protein coding gene Chr7:14225952-14244489 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029343
 protein coding gene Chr7:23880976-23899273 (+)
CAST/EiJ ENSTCUG00005049660
 protein coding gene Chr7:15921653-15940229 (+)
CBA/J ENSMUSG00210051498
 protein coding gene Chr7:15051888-15070422 (+)
DBA/2J ENSMUSG00185051931
 protein coding gene Chr7:18265651-18284185 (+)
FVB/NJ ENSMUSG00205022359
 protein coding gene Chr7:15062412-15080951 (+)
JF1/MsJ ENSUMUG00000053905
 protein coding gene Chr7:22562078-22580486 (+)
LP/J ENSMUSG00230052688
 protein coding gene Chr7:23539573-23558108 (+)
NOD/ShiLtJ ENSMUSG00190048089
 protein coding gene Chr7:14533958-14552362 (+)
NZO/HlLtJ ENSMUSG00225023520
 protein coding gene Chr7:22207460-22225994 (+)
PWK/PhJ ENSLUMG00010040174
 protein coding gene Chr7:14496541-14514994 (+)
SPRET/EiJ ENSMSPG00010050344
 protein coding gene Chr7:14157462-14175516 (+)
WSB/EiJ ENSIUOG00005051679
 protein coding gene Chr7:8999179-9017662 (+)



Homology
more
  • Human Ortholog
    PHLDB3, pleckstrin homology like domain family B member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHLDB3, pleckstrin homology like domain family B member 3
  • Links
    NCBI Gene ID: 653583
    UniProt: Q6NSJ2

  • Chr Location
    19q13.31; chr19:43473625-43505301 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074277 Ensembl Gene Model | MGI Sequence Detail 18535 C57BL/6J ±  kb
transcript ENSMUST00000206422 Ensembl | MGI Sequence Detail 2564 Not Applicable  
polypeptide ENSMUSP00000146187 Ensembl | MGI Sequence Detail 648 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR037810 PHLDB1/2/3, PH domain
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
    IPR052212 Pleckstrin homology-like domain-containing protein
  • GlyGen
    E9QAF4 2 sites
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGI:3641712
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:389486 Mouse Genome Informatics and Ensembl Genome Database Project, MGI Strain Genome Feature and Gene Model Load from Ensembl. Database Release. 2026;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory