Trav11 Gene Detail

Summary

• Symbol
  Trav11
• Name
  T cell receptor alpha variable 11
• Synonyms
  ENSMUSG00000072509, Gm10908

• Feature Type
  gene segment
• IDs
  MGI:3642163
  NCBI Gene: 100126466
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr14:53756760-53757316 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.40 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  2 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3642163	gene segment	Chr14:53756760-53757316 (+)
129S1/SvImJ	ENSMUSG00200043322	gene segment	Chr14:42290477-42291029 (+)
A/J	ENSMUSG00195025550	gene segment	Chr14:42088673-42089225 (+)
AKR/J	no annotation
BALB/cJ	ENSMUSG00180052875	gene segment	Chr14:42134477-42135029 (+)
BALB/cJ	ENSMUSG00180052868	gene segment	Chr14:41711119-41711671 (+)
C3H/HeJ	ENSMUSG00175052110	gene segment	Chr14:43816947-43817499 (+)
C3H/HeJ	ENSMUSG00175052102	gene segment	Chr14:43393614-43394166 (+)
C57BL/6NJ	ENSMUSG00215049274	gene segment	Chr14:42079296-42079852 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005049511	gene segment	Chr14:43896725-43897275 (+)
CBA/J	ENSMUSG00210047314	gene segment	Chr14:42066895-42067447 (+)
DBA/2J	ENSMUSG00185055996	gene segment	Chr14:46985702-46986254 (+)
DBA/2J	ENSMUSG00185056000	gene segment	Chr14:47592766-47593322 (+)
FVB/NJ	ENSMUSG00205048574	gene segment	Chr14:41405376-41405928 (+)
JF1/MsJ	ENSUMUG00000053906	gene segment	Chr14:58847002-58847554 (+)
LP/J	no annotation
NOD/ShiLtJ	ENSMUSG00190047288	gene segment	Chr14:41752786-41753338 (+)
NZO/HlLtJ	no annotation
PWK/PhJ	ENSLUMG00010049125	gene segment	Chr14:41703178-41703730 (+)
PWK/PhJ	ENSLUMG00010042006	gene segment	Chr14:41279939-41280491 (+)
SPRET/EiJ	ENSMSPG00010047425	gene segment	Chr14:45140469-45141025 (+)
WSB/EiJ	no annotation

Homology

• Human Ortholog
  TRAV10, T cell receptor alpha variable 10

• Vertebrate Orthologs
  18

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV10, T cell receptor alpha variable 10
  
• Synonyms
  TCRAV10S1, TCRAV24S1
• Links
  HGNC:12103

  NCBI Gene ID: 28676

  UniProt: A0A0B4J240

  
  
• Chr Location
  14q11.2; chr14:21825472-21826075 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav11 stringent orthology
  1 human;1 mouse;17 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV10
• Gene Tree
  Trav11
  

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000096615 (Evidence)
• NCBI Gene
  100126466

Representative Sequences			Length	Strain/Species
genomic	100126466	NCBI Gene Model | MGI Sequence Detail	557	C57BL/6J
polypeptide	A0A0B4J1J9	UniProt | EBI | MGI Sequence Detail	114	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• PDB
  4Y16, 4Y2D, 4Y4F, 4Y4H, 4Y4K, 4ZAK, 5VCJ, 6MIV, 6MIY, 6MJ4, 6MJ6, 6MJA, 6MJI, 6MJJ, 6MJQ, 8T4Z
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
  IPR051896 T cell receptor alpha variable region

References

• Summaries
  All 9
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
• Latest
  J:337059 Iwanami N, et al., Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR alpha chain of iNKT cells. Nat Commun. 2023 Jun 20;14(1):3645