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Prss3l Gene Detail
Summary
  • Symbol
    Prss3l
  • Name
    serine protease 3 like
  • Synonyms
    Gm10334
Location &
Maps
more
  • Sequence Map
    Chr6:41419150-41423079 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 19.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    208 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3641889
 protein coding gene Chr6:41419150-41438162 (-)
129S1/SvImJ ENSMUSG00200045200
 protein coding gene Chr6:38477052-38480978 (-)
A/J ENSMUSG00195034645
 protein coding gene Chr6:38446724-38450653 (-)
AKR/J ENSMUSG00220008935
 protein coding gene Chr6:38047524-38051451 (-)
BALB/cJ ENSMUSG00180043899
 protein coding gene Chr6:38575115-38579042 (-)
C3H/HeJ ENSMUSG00175043942
 protein coding gene Chr6:38402235-38406162 (-)
C57BL/6NJ ENSMUSG00215041910
 protein coding gene Chr6:38500914-38504843 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J ENSMUSG00210048077
 protein coding gene Chr6:38453987-38457914 (-)
DBA/2J ENSMUSG00185040777
 protein coding gene Chr6:38556491-38560418 (-)
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J ENSMUSG00230039967
 protein coding gene Chr6:39480173-39484100 (-)
NOD/ShiLtJ ENSMUSG00190047379
 protein coding gene Chr6:38345947-38349874 (-)
NZO/HlLtJ ENSMUSG00225018533
 protein coding gene Chr6:41462811-41466738 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PRSS1, serine protease 1
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS1, serine protease 1
  • Synonyms
    TRP1, TRY1, TRY4, TRYP1
  • Links
    NCBI Gene ID: 5644
    UniProt: P07477

  • Chr Location
    7q34; chr7:142749468-142753072 (+)  GRCh38
  • Human Ortholog
    PRSS2, serine protease 2
  • Synonyms
    TRY2, TRY8, TRYP2
  • Links
    NCBI Gene ID: 5645
    UniProt: P07478

  • Chr Location
    7q34; chr7:142760398-142774564 (+)  GRCh38
  • Human Ortholog
    PRSS3, serine protease 3
  • Synonyms
    MTG, PRSS4, T9, TRY3, TRY4
  • Links
    NCBI Gene ID: 5646
    UniProt: P35030

  • Chr Location
    9p13.3; chr9:33750679-33799231 (+)  GRCh38
  • Human Ortholog
    PRSS3P2, PRSS3 pseudogene 2
  • Synonyms
    T6, TRY6
  • Links
    NCBI Gene ID: 154754
    UniProt: Q8NHM4

  • Chr Location
    7q34
Human Diseases
more
  • Diseases
    1 with human PRSS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071517 Ensembl Gene Model | MGI Sequence Detail 3930 C57BL/6J ±  kb
transcript ENSMUST00000095999 Ensembl | MGI Sequence Detail 876 Not Applicable  
polypeptide ENSMUSP00000093698 Ensembl | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    3.4.21.1
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR018114 Serine protease-like, trypsin family, histidine active site
    IPR050127 Serine Proteases (Peptidase S1 Family)
    IPR001254 Serine proteases, trypsin domain
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less

  • Microarray probesets 1
Other
Accession IDs
less
MGI:7516367
References
more
  • Summaries
    All 15
    Gene Ontology 6
  • Earliest
    J:67100 Chen F, et al., Differential transcriptional regulation of individual TCR Vbeta segments before gene rearrangement. J Immunol. 2001 Feb 1;166(3):1771-80
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory