Defa-ps1 Pseudogene Detail

Summary

• Symbol
  Defa-ps1
• Name
  defensin, alpha, pseudogene 1
• Synonyms
  Crypi, Defcr-ps1, Defcr-ps26

• Feature Type
  pseudogene
• IDs
  MGI:3630392
  NCBI Gene: 727720
• Alliance
  genome feature page

Location &
Maps

• Sequence Map
  Chr8:22185028-22185869 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 10.35 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  32 from dbSNP Build 142
• Strain Annotations
  14

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3630392	pseudogene	Chr8:22185028-22185869 (+)
129S1/SvImJ	ENSMUSG00200033920	pseudogene	Chr8:17233284-17234125 (+)
A/J	ENSMUSG00195044294	pseudogene	Chr8:17784714-17785555 (+)
AKR/J	no annotation
BALB/cJ	ENSMUSG00180026978	pseudogene	Chr8:17309374-17310215 (+)
C3H/HeJ	no annotation
C57BL/6NJ	ENSMUSG00215030552	pseudogene	Chr8:17241126-17241967 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005019810	pseudogene	Chr8:17597479-17598311 (+)
CBA/J	ENSMUSG00210043920	pseudogene	Chr8:17309024-17309865 (+)
DBA/2J	ENSMUSG00185041350	pseudogene	Chr8:23111968-23112809 (+)
FVB/NJ	ENSMUSG00205032706	pseudogene	Chr8:16801872-16802713 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230011661	pseudogene	Chr8:26873171-26874012 (+)
NOD/ShiLtJ	ENSMUSG00190037810	pseudogene	Chr8:17342525-17343366 (+)
NZO/HlLtJ	ENSMUSG00225021579	pseudogene	Chr8:30481320-30482161 (+)
PWK/PhJ	no annotation
SPRET/EiJ	ENSMSPG00010015208	pseudogene	Chr8:17265039-17265880 (+)
WSB/EiJ	ENSIUOG00005021594	pseudogene	Chr8:18032014-18032855 (+)

Homology

• Gene Tree
  Defa-ps1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Defa-ps1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21
• RefSeq
  1

• Ensembl
  ENSMUSG00000095813 (Evidence)
• NCBI Gene
  727720

Representative Sequences			Length	Strain/Species
genomic	727720	NCBI Gene Model | MGI Sequence Detail	842	C57BL/6J
transcript	NR_003146	RefSeq | MGI Sequence Detail	282	Not Specified

Molecular
Reagents

• All nucleic 1

  Genomic 1

  
  

  Microarray probesets 6

Other
Accession IDs

MGD-MRK-16375, MGI:99593

References

• Summaries
  All 13

  Phenotypes 1
• Earliest
  J:16918 Huttner KM, et al., Structure and diversity of the murine cryptdin gene family. Genomics. 1994 Feb;19(3):448-53
• Latest
  J:332494 Dong X, et al., Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection. Immunity. 2022 Jul 15;55(9):1645-1662