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Mir497 Gene Detail
Summary
  • Symbol
    Mir497
  • Name
    microRNA 497
  • Synonyms
    Mirn497, mmu-mir-497
Location &
Maps
more
  • Sequence Map
    Chr11:70125543-70125626 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 42.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629886
 miRNA gene Chr11:70125543-70125626 (+)
129S1/SvImJ ENSMUSG00200050211
 miRNA gene Chr11:67072572-67072655 (+)
A/J ENSMUSG00195053156
 miRNA gene Chr11:67099057-67099140 (+)
AKR/J ENSMUSG00220054235
 miRNA gene Chr11:67208037-67208120 (+)
BALB/cJ ENSMUSG00180053876
 miRNA gene Chr11:67167610-67167693 (+)
C3H/HeJ ENSMUSG00175054532
 miRNA gene Chr11:67117831-67117914 (+)
C57BL/6NJ ENSMUSG00215055031
 miRNA gene Chr11:66894963-66895046 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007126
 miRNA gene Chr11:64985111-64985194 (+)
CAST/EiJ ENSTCUG00005053741
 miRNA gene Chr11:66659432-66659515 (+)
CBA/J ENSMUSG00210054380
 miRNA gene Chr11:66971879-66971962 (+)
DBA/2J ENSMUSG00185056833
 miRNA gene Chr11:67172111-67172194 (+)
FVB/NJ ENSMUSG00205053938
 miRNA gene Chr11:67063855-67063938 (+)
JF1/MsJ ENSUMUG00000057037
 miRNA gene Chr11:67570609-67570692 (+)
LP/J ENSMUSG00230053814
 miRNA gene Chr11:68282893-68282976 (+)
NOD/ShiLtJ ENSMUSG00190054188
 miRNA gene Chr11:67201790-67201873 (+)
NZO/HlLtJ ENSMUSG00225048169
 miRNA gene Chr11:70464344-70464427 (+)
PWK/PhJ ENSLUMG00010053694
 miRNA gene Chr11:67082002-67082085 (+)
SPRET/EiJ ENSMSPG00010049505
 miRNA gene Chr11:67804210-67804293 (+)
WSB/EiJ ENSIUOG00005052659
 miRNA gene Chr11:67096706-67096789 (+)



Homology
more
  • Human Ortholog
    MIR497, microRNA 497
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR497, microRNA 497
  • Synonyms
    hsa-mir-497, mir-497, MIRN497
  • Links
    NCBI Gene ID: 574456

  • Chr Location
    chr17:7017911-7018022 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MIR497 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit exacerbated DSS-induced colitis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    665
  • Tissues
    18
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      24
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 751537 NCBI Gene Model | MGI Sequence Detail 84 C57BL/6J ±  kb
    transcript NR_030444 RefSeq | MGI Sequence Detail 84 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 4
      Primer pair 2
      Other 2
    Other Database
    Links
    less
    miRBase MI0004636
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:361665 Ding Z, et al., DEmiRNA-mRNA regulatory network reveals miR-122-5p as a regulatory factor of arginine metabolism in necrotizing enterocolitis. Front Genet. 2024;15:1480431
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory