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Mir499 Gene Detail
Summary
  • Symbol
    Mir499
  • Name
    microRNA 499
  • Synonyms
    mir 499, Mirn499, mmu-mir-499
Location &
Maps
more
  • Sequence Map
    Chr2:155464800-155464878 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3629633
 miRNA gene Chr2:155464800-155464878 (+)
129S1/SvImJ ENSMUSG00200031560
 miRNA gene Chr2:152332687-152332765 (+)
A/J ENSMUSG00195023263
 miRNA gene Chr2:152692670-152692748 (+)
AKR/J ENSMUSG00220046600
 miRNA gene Chr2:151982176-151982254 (+)
BALB/cJ ENSMUSG00180049646
 miRNA gene Chr2:152163868-152163946 (+)
C3H/HeJ ENSMUSG00175051748
 miRNA gene Chr2:152907946-152908024 (+)
C57BL/6NJ ENSMUSG00215036456
 miRNA gene Chr2:152312426-152312504 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007766
 miRNA gene Chr2:147578568-147578646 (+)
CAST/EiJ ENSTCUG00005044041
 miRNA gene Chr2:151301295-151301373 (+)
CBA/J ENSMUSG00210017326
 miRNA gene Chr2:152844399-152844477 (+)
DBA/2J ENSMUSG00185050586
 miRNA gene Chr2:152525641-152525719 (+)
FVB/NJ ENSMUSG00205041373
 miRNA gene Chr2:151605304-151605382 (+)
JF1/MsJ ENSUMUG00000049313
 miRNA gene Chr2:152181759-152181837 (+)
LP/J ENSMUSG00230045665
 miRNA gene Chr2:154130587-154130665 (+)
NOD/ShiLtJ ENSMUSG00190045943
 miRNA gene Chr2:152233318-152233396 (+)
NZO/HlLtJ ENSMUSG00225005301
 miRNA gene Chr2:162161968-162162046 (+)
PWK/PhJ ENSLUMG00010046382
 miRNA gene Chr2:152126258-152126336 (+)
SPRET/EiJ ENSMSPG00010037369
 miRNA gene Chr2:154922646-154922724 (+)
WSB/EiJ ENSIUOG00005048556
 miRNA gene Chr2:151919476-151919554 (+)



Homology
more
  • Human Ortholog
    MIR499A, microRNA 499a
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR499A, microRNA 499a
  • Synonyms
    hsa-mir-499a, MIR499, mir-499a, MIRN499
  • Links
    NCBI Gene ID: 574501

  • Chr Location
    chr20:34990376-34990497 (+)  GRCh38
Human Diseases
more
  • Diseases
    4 with human MIR499A associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit no overt abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    662
  • Tissues
    21
  • Literature Summary
    4
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 735275 NCBI Gene Model | MGI Sequence Detail 79 C57BL/6J ±  kb
transcript NR_030757 RefSeq | MGI Sequence Detail 79 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Primer pair 2
    Other 3
Other Database
Links
less
miRBase MI0004676
References
more
  • Summaries
    All 27
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:377389 Wu J, et al., Long noncoding RNA ZFAS1 suppresses osteogenic differentiation of bone marrow-derived mesenchymal stem cells by upregulating miR-499-EPHA5 axis. Mol Cell Endocrinol. 2022 Jan 1;539:111490
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory